Evidence map›Paper›PMID 37920423›Full record

ReviewCureus2023

Duct-to-Duct Anastomosis Versus Bilioenteric Anastomosis for Pediatrics Living Donor Liver Transplantation: A Systematic Review and Meta-Analysis.

Beshoy Effat Elkomos, Philopateer Alkomos, Rao Junaid Saleem, Joseph Hanna, Guirgis Ebeidallah, Philobater B Awad, Basma Hassan, Ahmed Ghazal, Amr Abdelaal

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Safety and feasibility of duct-to-duct biliary anastomosis in pediatric liver transplantation: A single-center retrospective study.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Beshoy Effat ElkomosGeneral and Emergency Surgery, Northwick Park Hospital, London Northwest NHS Trust, London, GBR.
Philopateer AlkomosMedicine, Ain Shams University, Cairo, EGY.
Rao Junaid SaleemGeneral and Emergency Surgery, Northwick Park Hospital, London Northwest NHS Trust, London, GBR.
Joseph HannaGeneral Surgery, Wirral University Hospital, Cheshire, GBR.
Guirgis EbeidallahTrauma, Orthopedics and Plastics Surgery, Salford Royal Hospital NHS Trust, Salford, GBR.
Philobater B AwadGeneral Surgery, Ain Shams University, Cairo, EGY.
Basma HassanGeneral Surgery, Ain Shams University, Cairo, EGY.
Ahmed GhazalOrthopedics, Northwick Park Hospital, London Northwest NHS Trust, London, GBR.
Amr AbdelaalGeneral Surgery, Ain Shams University, Cairo, EGY.
Cheshire West and Chester · GBSalford Royal Hospital · GBNorthwick Park Hospital · GBLondon North West Healthcare NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With an incidence exceeding 30%, biliary complications after pediatric liver transplantation remain a great challenge. In addition, the database includes numerous controversial papers about the safety of duct-to-duct anastomosis compared to Reux-en-Y hepaticojejunostomy for pediatric living donor liver transplantation (LDLT). We aim to compare the two techniques in pediatric LDLT by conducting a systematic review and meta-analysis. PUBMED, Web of Science, Scopus, and Cochrane Library were searched for eligible studies from 1989 to October 2022. According to our eligibility criteria, seven articles (561 pediatric LDLT) were included in our study. On one hand, DD anastomosis is associated with a higher rate of biliary stricture in comparison to RYHJ (OR: 2.47, 95% CI = 1.20-5.09, P = 0.01; I2 = 12%). On the other hand, the incidence of cholangitis was higher in RYHJ (OR: 0.10 95% CI = 0.01- 0.84, P = 0.03; I2 = 0%). However, there was no significant difference in the overall incidence of complications, leakage and mortality between the two groups (overall incidence of complication OR: 1.12, 95% CI = 0.34-3.68, P = 0.86; I2 = 62%), (Leakage OR: 2.22, 95% CI = 0.79-6.23, P = 0.13; I2 = 18%) and (Mortality OR: 2.53, 95% CI = 0.61-10.57, P = 0.30; I2 = 0%). In conclusion, with a lower incidence of cholangitis, an equal overall incidence of biliary complication, and the possibility of RY conversion in case of stricture, DD anastomosis offers a feasible, safe, and more physiological alternative to RYHJ for pediatric LDLT.

Indexed as

biliary anastomosisbiliary reconstructioninfantliver transplantationpediatric ldlt

Identifiers

PMID37920423
PMCPMC10619589
OpenAlexW4388130294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.