Evidence map›Paper›PMID 37920356›Full record

ArticleChemical science2023

A cellular platform for production of C

Matthew A Davis, Vivian Yaci Yu, Beverly Fu, Miao Wen, Edward J Koleski, Joshua Silverman, Charles A Berdan, Daniel K Nomura, Michelle C Y Chang

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Matthew A DavisDepartment of Molecular & Cellular Biology, University of California Berkeley CA 94720-3200 USA mcchang@berkeley.edu.
Vivian Yaci YuDepartment of Molecular & Cellular Biology, University of California Berkeley CA 94720-3200 USA mcchang@berkeley.edu.
Beverly FuDepartment of Chemistry, University of California Berkeley CA 94720-1460 USA.ORCID https://orcid.org/0000-0002-2345-6911
Miao WenDepartment of Chemistry, University of California Berkeley CA 94720-1460 USA.
Edward J KoleskiDepartment of Chemistry, University of California Berkeley CA 94720-1460 USA.
Joshua SilvermanCalysta 1900 Alameda de las Pulgas Suite 200 San Mateo CA 94404 USA.
Charles A BerdanDepartment of Chemistry, University of California Berkeley CA 94720-1460 USA.
Daniel K NomuraDepartment of Molecular & Cellular Biology, University of California Berkeley CA 94720-3200 USA mcchang@berkeley.edu.ORCID https://orcid.org/0000-0003-1614-8360
Michelle C Y ChangDepartment of Molecular & Cellular Biology, University of California Berkeley CA 94720-3200 USA mcchang@berkeley.edu.ORCID https://orcid.org/0000-0003-3747-7630
University of California, Berkeley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Living organisms carry out a wide range of remarkable functions, including the synthesis of thousands of simple and complex chemical structures for cellular growth and maintenance. The manipulation of this reaction network has allowed for the genetic engineering of cells for targeted chemical synthesis, but it remains challenging to alter the program underlying their fundamental chemical behavior. By taking advantage of the unique ability of living systems to use evolution to find solutions to complex problems, we have achieved yields of up to ∼95% for three C

Identifiers

PMID37920356
PMCPMC10619544
OpenAlexW4387464217

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.