Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 8 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors at 4 institutions in 1 country.
Xiao LuoShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University Dongchuan Road 500 Shanghai 200241 China xluo@chem.ecnu.edu.cn ytian@chem.ecnu.edu.cn xhqian@ecnu.edu.cn.ORCID https://orcid.org/0000-0002-2561-6114
Zhonghui ZhangShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University Dongchuan Road 500 Shanghai 200241 China xluo@chem.ecnu.edu.cn ytian@chem.ecnu.edu.cn xhqian@ecnu.edu.cn.
Jie WangDepartment of Molecular and Cellular Biochemistry, School of Medicine, Shanghai Jiaotong University Chongqing South Road 280 Shanghai 200025 China yangwen@shsmu.edu.cn.
Xueli WangState Key Laboratory of Precision Spectroscopy, East China Normal University Dongchuan Road 500 Shanghai 200241 China.
Yani ZhangInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine Cailun Road 1200 Shanghai 201203 China.
Jinquan ChenState Key Laboratory of Precision Spectroscopy, East China Normal University Dongchuan Road 500 Shanghai 200241 China.ORCID https://orcid.org/0000-0003-0652-1379
Guangbo GeInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine Cailun Road 1200 Shanghai 201203 China.ORCID https://orcid.org/0000-0002-8437-9155
Wen YangDepartment of Molecular and Cellular Biochemistry, School of Medicine, Shanghai Jiaotong University Chongqing South Road 280 Shanghai 200025 China yangwen@shsmu.edu.cn.
Xuhong QianShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University Dongchuan Road 500 Shanghai 200241 China xluo@chem.ecnu.edu.cn ytian@chem.ecnu.edu.cn xhqian@ecnu.edu.cn.
Yang TianShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University Dongchuan Road 500 Shanghai 200241 China xluo@chem.ecnu.edu.cn ytian@chem.ecnu.edu.cn xhqian@ecnu.edu.cn.ORCID https://orcid.org/0000-0001-8850-0349
Youjun YangState Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology Meilong Road 130 Shanghai 200237 China youjunyang@ecust.edu.cn.ORCID https://orcid.org/0000-0001-7085-6048
East China Normal University · CNEast China University of Science and Technology · CNShanghai Jiao Tong University · CNShanghai University of Traditional Chinese Medicine · CN
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
The biological function of radicals is a broad continuum from signaling to killing. Yet, biomedical exploitation of radicals is largely restricted to the theme of healing-by-killing. To explore their potential in healing-by-signaling, robust radical generation methods are warranted. Acyl radicals are endogenous, exhibit facile chemistry and elicit matrix-dependent biological outcomes. Their implications in health and disease remain untapped, primarily due to the lack of a robust generation method with spatiotemporal specificity. Fusing the Norrish chemistry into the xanthene scaffold, we developed a novel general and modular molecular design strategy for photo-triggered generation of acyl radicals,
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Acyl-caged rhodamines: photo-controlled and self-calibrated generation of acetyl radicals for neural function recovery in early AD mice. · full record | OpenQuestion