ArticleChemical science2023
Computer vision as a new paradigm for monitoring of solution and solid phase peptide synthesis.
Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- When chemistry is too colourful: gamut clipping in 8-bit sRGB risks misinterpretation of camera-based chemical analysis.Digital discovery · 2026Article
- Computer Vision Enables Monitoring and Kinetic Analysis of Structurally Diverse Carbon Monoxide Surrogates.Angewandte Chemie (International ed. in English) · 2026Article
- From Eyes to Cameras to Kinetics: Computer Vision for Chemical Process Monitoring.Accounts of chemical research · 2026Article
- Computer Vision Helps Experimentally Monitor Mixing Effects in Deep Eutectic Solvents.ACS sustainable chemistry & engineering · 2025Article
- Presumptive Tests for Xylazine-A Computer Vision Approach.Analytical science advances · 2025Article
- Parallel and High Throughput Reaction Monitoring with Computer Vision.Angewandte Chemie (International ed. in English) · 2025Article
- A Computer Vision Approach toward Verifying CFD Models of Stirred Tank Reactors.Organic process research & development · 2024Article
- Keeping an "eye" on the experiment: computer vision for real-time monitoring and control.Chemical science · 2024Article
- Computer vision as a new paradigm for monitoring of solution and solid phase peptide synthesis.Chemical science · 2023Article
- Teaching old presumptive tests new digital tricks with computer vision for forensic applications.Digital discovery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
We report a strategy for the camera-enabled non-contact colourimetric reaction monitoring and optimisation of amide bond formation, mediated by coupling reagents. For amide bond formation in solution phase, investigation of reactions mediated by HATU, PyAOP, and DIC/Oxyma evidenced correlations between colour parameters extracted from video data and conversion to amide product measured by off-line HPLC analysis of concentration. These correlations, supported by mutual information analysis, were further investigated using video recordings of solid phase peptide synthesis (SPPS), co-analysed by off-line HPLC to track remaining unreacted substrate in solution. An optimisation method of coupling time in SPPS was derived from Δ
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.