Evidence map›Paper›PMID 37920232›Full record

ArticleACI open2021

Facilitating Genetics Aware Clinical Decision Support: Putting the eMERGE Infrastructure into Practice.

Casey Overby Taylor, Luke V Rasmussen, Laura J Rasmussen-Torvik, Cynthia A Prows, David A Dorr, Lipika Samal, Samuel Aronson

Abstract read
In one paragraph

Article in ACI open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Casey Overby TaylorDepartments of Medicine and Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States.
Luke V RasmussenDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois, United States.
Laura J Rasmussen-TorvikDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois, United States.
Cynthia A ProwsDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States.
David A DorrDepartments of Medical Informatics and Clinical Epidemiology and Medicine, Oregon Health & Science University, Portland, Oregon, United States.
Lipika SamalDepartment of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States.
Samuel AronsonPartners Personalized Medicine, Partners HealthCare, Cambridge, Massachusetts, United States.

Funding

Genomic Basis of Susceptibility to COVID-19 Infection and its ComplicationsU01HG006379 · NHGRI · MAYO CLINIC ROCHESTER · PI Richard R. Sharp · 2011 to 2026
$16.5M
Global Alliance for Genomic Health (GA4GH)U01HG008676 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI LENNON, NIALL JOHN, REHM, HEIDI L · 2015 to 2019
$8.6M
OMOP information model for eMERGE phenotypingU01HG008679 · NHGRI · GEISINGER CLINIC · PI WILLIAMS, MARC S. · 2015 to 2019
$4.4M
Better Outcomes for Children: Promoting Excellence in Healthcare Genomics to Inform PolicyU01HG008666 · NHGRI · CINCINNATI CHILDRENS HOSP MED CTR · PI HARLEY, JOHN BARKER · 2015 to 2019
$4.2M
Genomic Medicine at Northwestern: Discovery and ImplementationU01HG008673 · NHGRI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CHISHOLM, REX L, SMITH, MAUREEN E · 2015 to 2019
$4.1M
Clinical Decision Support for Unsolicited Genomic ResultsR35HG010714 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI TAYLOR, CASEY OVERBY · 2020 to 2024
$2.8M
NHGRI NIH HHS R35 HG010714NHGRI NIH HHS U01 HG006379NHGRI NIH HHS U01 HG008666NHGRI NIH HHS U01 HG008673NHGRI NIH HHS U01 HG008676NHGRI NIH HHS U01 HG008679
6 · The paper itself

Abstract

This editorial provides context for a series of published case reports in ACI Open by summarizing activities and outputs of joint electronic health record integration and pharmacogenomics workgroups in the NIH-funded electronic Medical Records and Genomics (eMERGE) Network. A case report is a useful tool to describe the range of capabilities that an IT infrastructure or a particular technology must support. The activities we describe have informed infrastructure requirements used during eMERGE phase III, provided a venue to share experiences and ask questions among other eMERGE sites, summarized potential hazards that might be encountered for specific clinical decision support (CDS) implementation scenarios, and provided a simple framework that captured progress toward implementing CDS at eMERGE sites in a consistent format.

Indexed as

case reportclinical decision support requirementseditorialgathering information technologygenomicsinfrastructurepharmacogenomics

Identifiers

PMID37920232
PMCPMC10621326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.