ReviewCell surface (Amsterdam, Netherlands)2023
Alternative mechanisms of action of metallic nanoparticles to mitigate the global spread of antibiotic-resistant bacteria.
Review in Cell surface (Amsterdam, Netherlands), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Antimicrobial Resistance as a Global Public Health Challenge: Epidemiological Burden, Bioethical Dimensions and Emerging Therapeutic Strategies.Infectious disease reports · 2026Review
- Biogenic Silver Nanoparticles Synthesised Using Staphylococcus saprophyticus Cell-Free Supernatant Exhibit Potent Antimicrobial Activities via Oxidative Stress.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Article
- Green-synthesized quantum dots from quercus brantii for infected polymicrobial wound healing: mechanisms and biocompatibility.BMC biotechnology · 2026Article
- Bacterial Adaptive Responses to Green and Chemically Synthesized Silver Nanoparticles: Implications for Resistance Development.Nanomaterials (Basel, Switzerland) · 2026Article
- Nanoparticle-Based Strategies to Combat Multidrug-Resistant Bacteria: Mechanisms, Applications, and Future Perspectives.MicrobiologyOpen · 2026Review
- The Multifaceted Mechanistic Actions of Antimicrobial Nanoformulations: Overcoming Resistance and Enhancing Efficacy.Pharmaceutics · 2026Review
- Calcium Phosphate Nanostructured Biocomposites with Applications in Bone Tissue Engineering.Materials (Basel, Switzerland) · 2026Review
- Veterinary Drug Residues in Food Chains: Sources, Exposure Pathways, Health Impacts, Mitigation, and Safety Assurance.Foods (Basel, Switzerland) · 2026Review
- Biogenic Silver-Selenium nanocomposite with anticancer activity and potent efficacy against vancomycin-resistant Staphylococcus aureus.PloS one · 2026Article
- Article
- Green-Synthesized Nanomaterials for Water Disinfection: Mechanisms, Efficacy, and Environmental Safety.Nanomaterials (Basel, Switzerland) · 2025Review
- Targeting Bacterial Biofilms on Medical Implants: Current and Emerging Approaches.Antibiotics (Basel, Switzerland) · 2025Review
- In Vitro Study on Nematicidal Effect of Silver Nanoparticles AgainstMolecules (Basel, Switzerland) · 2025Article
- Review
- Biosynthesis of silver nanoparticles from macroalgae Hormophysa triquetra and investigation of its antibacterial activity and mechanism against pathogenic bacteria.Scientific reports · 2025Article
- Silver nanoparticles as next-generation antimicrobial agents: mechanisms, challenges, and innovations against multidrug-resistant bacteria.Frontiers in cellular and infection microbiology · 2025Review
- Antibacterial property of lead telluride quantum dot layer fabricated on glass substrate.PloS one · 2025Article
- Nanotechnology for fungal pathogen control in crops: innovations, public health impacts, and disease prevention.Frontiers in fungal biology · 2025Review
- Biosynthesis and biological activities of magnesium hydroxide nanoparticles using Tinospora cordifolia leaf extract.Bioprocess and biosystems engineering · 2024Article
- Colistin Resistance Mechanism and Management Strategies of Colistin-ResistantPathogens (Basel, Switzerland) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the biggest issues for medical professionals and a serious global concern is the emergence of multi-drug-resistant bacteria, which is the result of the overuse or misuse of antimicrobial agents. To combat this urgent problem, new drugs with alternative mechanisms of action are continuously replacing conventional antimicrobials. Nanotechnology-fueled innovations provide patients and medical professionals with hope for overcoming drug resistance. The aim of the present work was to document the antimicrobial potential and mechanisms of action of metallic nanoparticles against bacterial pathogens. Cell wall interaction and membrane penetration, reactive oxygen species (ROS) production, DNA damage, and protein synthesis inhibition were some of the generalised mechanisms recognised in the current study. In vitro and in vivo studies demonstrated that toxicity concerns and the development of bacterial resistance against nanoparticles (NPs) harden the use of metallic NP products for the treatment of drug-resistant bacterial pathogens. Therefore, researchers across the globe should actively engage in solving the above-mentioned issues.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.