Evidence map›Paper›PMID 37919679›Full record

ArticleBMC nephrology2023

Management and outcomes of myocardial infarction in people with impaired kidney function in England.

Jemima Scott, Patrick Bidulka, Dominic M Taylor, Udaya Udayaraj, Fergus J Caskey, Kate Birnie, John Deanfield, Mark de Belder, Spiros Denaxas, Clive Weston and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  6. Long live the kidney despite every threats: a case report.The Pan African medical journal · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Jemima Scott *Population Health Sciences, University of Bristol, Bristol, England. Jemima.scott@bristol.ac.uk.
Patrick Bidulka *Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, Keppel Street, London, England.
Dominic M TaylorPopulation Health Sciences, University of Bristol, Bristol, England.
Udaya UdayarajOxford Kidney Unit, Churchill Hospital, Oxford, England.
Fergus J CaskeyPopulation Health Sciences, University of Bristol, Bristol, England.
Kate BirniePopulation Health Sciences, University of Bristol, Bristol, England.
John DeanfieldNational Institute for Cardiovascular Outcomes Research (NICOR), NHS Arden & Greater East Midlands Commissioning Support Unit, Leicester, England.
Mark de BelderNational Institute for Cardiovascular Outcomes Research (NICOR), NHS Arden & Greater East Midlands Commissioning Support Unit, Leicester, England.
Spiros DenaxasBritish Heart Foundation, Data Science Centre, London, UK.
Clive WestonGlangwili General Hospital, Dolgwili Road, Carmarthen, Wales, UK.
David Adlam *Department of Cardiovascular Sciences, University of Leicester, and NIHR Leicester Biomedical Research Centre, Leicester, UK.
Dorothea Nitsch *Department of Non-Communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, Keppel Street, London, England.
London School of Hygiene & Tropical Medicine · GBNIHR Research Delivery Network · GBNorth Bristol NHS Trust · GBUniversity of Bristol · GBGlangwili General Hospital · GBUCL Biomedical Research Centre · GBUniversity of Leicester · GBUniversity of Oxford · GB

Funding

British Heart Foundation SP/16/5/32415Cancer Research UK C53325/A21134Medical Research Council MC_PC_20030Medical Research Council MC_PC_20051Medical Research Council MC_PC_20059
6 · The paper itself

Abstract

backgroundAcute myocardial infarction (AMI) causes significant mortality and morbidity in people with impaired kidney function. Previous observational research has demonstrated reduced use of invasive management strategies and inferior outcomes in this population. Studies from the USA have suggested that disparities in care have reduced over time. It is unclear whether these findings extend to Europe and the UK.

methodsLinked data from four national healthcare datasets were used to investigate management and outcomes of AMI by estimated glomerular filtration rate (eGFR) category in England. Multivariable logistic and Cox regression models compared management strategies and outcomes by eGFR category among people with kidney impairment hospitalised for AMI between 2015-2017.

resultsIn a cohort of 5 835 people, we found reduced odds of invasive management in people with eGFR < 60mls/min/1.73m

conclusionsIn England, patients with reduced eGFR are less likely to receive invasive management compared to those with preserved eGFR. Disparities in care may however be decreasing over time, with the least difference seen in patients with STEMI managed via the primary percutaneous coronary intervention pathway. Reduced eGFR continues to be associated with worse outcomes after AMI.

Indexed as

Myocardial InfarctionPercutaneous Coronary InterventionRenal InsufficiencyST Elevation Myocardial InfarctionHumansKidneyRisk FactorsTreatment OutcomeCKDCoronary angiographyMyocardial infarctionPercutaneous coronary interventionSurvival analysis

Identifiers

PMID37919679
PMCPMC10623815
OpenAlexW4388215019

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.