Evidence map›Paper›PMID 37919477›Full record

ArticleNatural products and bioprospecting2023

Three previously undescribed metabolites from Cordyceps cicadae JXCH-1, an entomopathogenic fungus.

Jing Fan, Pai Liu, Kuan Zhao, He-Ping Chen

Abstract read
In one paragraph

Article in Natural products and bioprospecting, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing Fan *School of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China.
Pai Liu *School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Kuan ZhaoCollege of Life Science, Jiangxi Science & Technology Normal University, Nanchang, 330013, China. 1020160918@jxstnu.edu.cn.
He-Ping ChenSchool of Pharmaceutical Sciences, South-Central Minzu University, Wuhan, 430074, China. chenhp@mail.scuec.edu.cn.ORCID http://orcid.org/0000-0003-0416-9535

Funding

Fundamental Research Funds for the Central Universities, South-Central Minzu University CPT22033National Natural Science Foundation of China 81903512
6 · The paper itself

Abstract

Three previously undescribed compounds, cordycicadione (1), cordycicadin F (2), and 7-hydroxybassiatin (3), were isolated from the cultures of Cordyceps cicadae JXCH1, an entomopathogenic fungus. Their structures and relative configurations were elucidated primarily by NMR spectroscopic analysis. The absolute configurations of 1 and 2 were determined by ECD calculations. Single-crystal X-ray diffraction method was adopted to determine the absolute configuration of 3. Compound 2 is a polycyclic polyketide with an unusual enol ether moiety and a spiro ring. The compounds obtained in this study were subjected to screening their inhibition against the proliferation of the human lung cancer cell line A549 and the production of nitric oxide in murine macrophages RAW264.7.

Indexed as

Cordyceps cicadaeCyclic dipeptideInsect pathogenic fungusPolyketideSteroid

Identifiers

PMID37919477
PMCPMC10622384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.