Evidence map›Paper›PMID 37919391›Full record

ArticleScientific reports2023

Daeshiho-tang attenuates inflammatory response and oxidative stress in LPS-stimulated macrophages by regulating TLR4/MyD88, NF-κB, MAPK, and Nrf2/HO-1 pathways.

Yong Jin Oh, Seong Eun Jin, Hyeun-Kyoo Shin, Hyekyung Ha

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  4. Anti-Inflammatory and Skin-Lightening Activities of Exosomes Derived fromJournal of microbiology and biotechnology · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yong Jin OhKM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea.
Seong Eun JinKM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea.
Hyeun-Kyoo ShinKM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea.
Hyekyung HaKM Science Research Division, Korea Institute of Oriental Medicine, 1672 Yuseong-daero, Yuseong-Gu, Daejeon, 34054, Korea. hkha@kiom.re.kr.
Korea Institute of Oriental Medicine · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Daeshiho-tang (DSHT), a traditional herbal formula with diverse pharmacological effects, has shown promise in medicine owing to its anti-hypertensive, anti-diabetic, and anti-inflammatory properties. However, the precise molecular mechanism underlying these effects remains unclear. Thus, we investigated the effect of DSHT on inflammatory response and oxidative stress to understand its molecular mechanism using lipopolysaccharide (LPS)-induced macrophage (RAW 264.7) cells. DSHT decreased the contents of nitric oxide (NO) and prostaglandin E

Indexed as

LipopolysaccharidesNF-kappa BAnimalsAnti-Inflammatory AgentsCyclooxygenase 2MacrophagesMiceMyeloid Differentiation Factor 88NF-E2-Related Factor 2Nitric Oxide Synthase Type IIOxidative StressRAW 264.7 CellsToll-Like Receptor 4Anti-Inflammatory AgentsCyclooxygenase 2LipopolysaccharidesMyeloid Differentiation Factor 88NF-E2-Related Factor 2NF-kappa BNitric Oxide Synthase Type IIToll-Like Receptor 4

Identifiers

PMID37919391
PMCPMC10622541
OpenAlexW4388232289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.