ReviewNature reviews. Disease primers2023
Congenital lung malformations.
Review in Nature reviews. Disease primers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
81 citing papers in PubMed, 3 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Efficacy of lobectomy versus segmentectomy for congenital lung malformations: a systematic review and meta-analysis.Pediatric surgery international · 2026Pooled it
- ESR Essentials: imaging of common paediatric pulmonary diseases-practice recommendations by the European Society of Paediatric Radiology.European radiology · 2025Guideline
- Risk of malignant transformation and infections in congenital lung malformations in adults: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025Pooled it
- Impact of prior pulmonary infection on surgical outcomes in pediatric pulmonary sequestration: a multicenter retrospective study from the East Asia Pediatric Surgery Research Consortium.Pediatric surgery international · 2026Article
- Retroperitoneal Ectopic Bronchogenic Cyst Mimicking an Adrenal Mass: A Case Report and Literature Review.The American journal of case reports · 2026Review
- Surgical Management of Congenital Lung Malformations: Indications, Timing, and Outcomes.Journal of chest surgery · 2026Review
- Management and outcomes of congenital pulmonary airway malformations and bronchopulmonary sequestrations diagnosed in the fetal period.Pediatric surgery international · 2026Article
- Congenital pulmonary airway malformation mimicking lung cancer in adults: a pitfall in oncologic diagnosis.Quantitative imaging in medicine and surgery · 2026Article
- Composition and Function of Decellularized Human Lung Extracellular Matrix from Congenital Pulmonary Airway Malformation.Journal of clinical medicine · 2026Article
- Thoracoscopic surgery for congenital pulmonary malformations in infants: a preliminary comparative evaluation of virtual reality-guided preoperative planning versus standard imaging.Surgical endoscopy · 2026Article
- Article
- An extremely rare case of congenital pulmonary airway malformation (CPAM) and atypical adenomatous hyperplasia (AAH) with EGFR mutation in a five-year-old girl.BMC pediatrics · 2026Article
- Application of a uniaxial force by pulling the skin around the mammary gland may affect the orientation of the ducts and the length of the mammary ductal network: Findings from computational modeling and laboratory experiments.PLoS computational biology · 2026Article
- Alphabet soup: a systematic approach to understanding congenital chest lesions.Pediatric radiology · 2026Review
- Endovascular Embolization of Pulmonary Sequestration in Children with Contraindications to Surgery: A Two-Centre Experience with Long-Term Follow-Up.Children (Basel, Switzerland) · 2026Article
- 25 years of surgery in patients with congenital lung malformations: the Rotterdam experience.Pediatric surgery international · 2026Article
- Thirty-year nationwide research on epidemiology, treatment, and outcomes of congenital lung malformations.Scientific reports · 2026Article
- Congenital Pulmonary Airway Malformations in Children: Beyond the Pulmonary Cystic Lesion Is There Really an Associated Laryngo-Tracheal Abnormality?Pediatric pulmonology · 2026Review
- Article
- Congenital Pulmonary Airway Malformation Volume Ratio in Fetuses With Congenital Cystic Lung Diseases to Predict Surgery Within 7 Days of Birth.The journal of obstetrics and gynaecology research · 2026Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital lung malformations (CLMs) are rare developmental anomalies of the lung, including congenital pulmonary airway malformations (CPAM), bronchopulmonary sequestration, congenital lobar overinflation, bronchogenic cyst and isolated congenital bronchial atresia. CLMs occur in 4 out of 10,000 live births. Postnatal presentation ranges from an asymptomatic infant to respiratory failure. CLMs are typically diagnosed with antenatal ultrasonography and confirmed by chest CT angiography in the first few months of life. Although surgical treatment is the gold standard for symptomatic CLMs, a consensus on asymptomatic cases has not been reached. Resection, either thoracoscopically or through thoracotomy, minimizes the risk of local morbidity, including recurrent infections and pneumothorax, and avoids the risk of malignancies that have been associated with CPAM, bronchopulmonary sequestration and bronchogenic cyst. However, some surgeons suggest expectant management as the incidence of adverse outcomes, including malignancy, remains unknown. In either case, a planned follow-up and a proper transition to adult care are needed. The biological mechanisms through which some CLMs may trigger malignant transformation are under investigation. KRAS has already been confirmed to be somatically mutated in CPAM and other genetic susceptibilities linked to tumour development have been explored. By summarizing current progress in CLM diagnosis, management and molecular understanding we hope to highlight open questions that require urgent attention.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.