Evidence map›Paper›PMID 37919239›Full record

ArticleObesity (Silver Spring, Md.)2023

Use and continuity of weight-modifying medications among adults with diabetes and overweight/obesity: US population study.

Rodolfo J Galindo, Tegveer S Uppal, Rozalina G McCoy, Guillermo E Umpierrez, Mohammed K Ali

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Observational
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Rodolfo J GalindoDivision of Endocrinology, University of Miami Miller School of Medicine & Diabetes Research Institute, Miami, Florida, USA.ORCID 0000-0002-9295-3225
Tegveer S UppalHubert Department of Global Health, Emory University Rollins School of Public Health, Atlanta, Georgia, USA.
Rozalina G McCoyMayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Rochester, Minnesota, USA.ORCID 0000-0002-2289-3183
Guillermo E UmpierrezDivision of Endocrinology, Emory University School of Medicine, Grady Memorial Hospital, Atlanta, Georgia, USA.ORCID 0000-0002-3252-5026
Mohammed K AliHubert Department of Global Health, Emory University Rollins School of Public Health, Atlanta, Georgia, USA.ORCID 0000-0001-7266-2503

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Use of Continuous Glucose Monitoring (CGM) in End-Stage Renal Disease(ESRD) Patients with Type 2 DiabetesK23DK123384 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALINDO, RODOLFO · 2020 to 2024
$934k
Predicting the Risk of Severe Hypoglycemic and Hyperglycemic Events in Adults with DiabetesK23DK114497 · NIDDK · MAYO CLINIC ROCHESTER · PI MCCOY, ROZALINA GRUBINA · 2017 to 2021
$846k
Community Paramedicine Program to Improve Diabetes Management among Adults Experiencing Severe HypoglycemiaR03DK127010 · NIDDK · MAYO CLINIC ROCHESTER · PI MCCOY, ROZALINA GRUBINA · 2021 to 2022
$239k
NCATS NIH HHS UL1 TR002378NIDDK NIH HHS 2P30DK111024NIDDK NIH HHS K23 DK114497NIDDK NIH HHS K23DK114497NIDDK NIH HHS K23 DK123384NIDDK NIH HHS K23DK123384NIDDK NIH HHS P30 DK111024NIDDK NIH HHS R03 DK127010NIDDK NIH HHS R03DK127010
6 · The paper itself

Abstract

objectiveTrends in use and continuity of use of diabetes-specific and non-diabetes weight-reducing (WR), weight-inducing (WI), and weight-neutral (WN) medications were examined among US adults with diabetes and overweight/obesity.

methodsSerial cross-sectional data from Medical Expenditure Panel Surveys (2010-2019) for adults (≥18 years) with diabetes and BMI ≥27 kg/m

resultsAmong 7402 US adults with diabetes and overweight/obesity (mean age 60.0 years [SD 13], 50% female), 64.9% of participants used any WI medications, decreasing from 68.9% (95% CI: 64.3%-73.5%) in 2010 to 58.6% (95% CI: 54.7%-62.5%) in 2019. It was estimated that 13.5% used WR medications, increasing 3.31-fold, from 6.4% (95% CI: 4.1%-8.7%) to 21.2% (95% CI: 18.0%-24.4%) and that 73.1% used WN medications, ranging from 70.5% (95% CI: 66.5-74.6) to 75.0% (95% CI: 71.7%-78.4%). Among adults using diabetes-specific WI (53.7%), WR (7.1%), and WN (62.4%) medications during the first year, 7.3%, 16.4%, and 9.0% discontinued it in the second year, respectively.

conclusionsOver 2010-2019, 64.9% of adults with diabetes and overweight/obesity were treated with WI medications, 13.5% with WR medications, and 73.1% with WN medications. Discontinuation of WR medications was nearly twice that of WI medications.

Indexed as

Diabetes MellitusOverweightAdultBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedObesityWeight Loss

Identifiers

PMID37919239
PMCPMC10840906

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.