Evidence map›Paper›PMID 37918938›Full record

ArticleAJNR. American journal of neuroradiology2023

Clinical Outcomes and Safety Comparison of Vertebroplasty, Balloon Kyphoplasty, and Vertebral Implant for Treatment of Vertebral Compression Fractures.

Taibo Li, Sharon Pang, Ryan England, Anna Gong, David Botros, Sasicha Manupipatpong, Ferdinand K Hui, Majid Khan

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Sphereplasty with 3D porous titanium microspheres for thoracolumbar vertebral compression fractures: analysis of clinical efficacy and safety profile of a novel technique.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Taibo LiFrom the Department of Biomedical Engineering (T.L.), Johns Hopkins School of Medicine, Baltimore, Maryland taiboli@jhu.edu.ORCID 0000-0002-6624-9293
Sharon PangDepartment of Emergency Medicine (S.P.), Massachusetts General Hospital, Boston, Massachusetts.
Ryan EnglandRussell H. Morgan Department of Radiology and Radiological Science (R.E., F.K.H.), The Johns Hopkins Hospital, Baltimore, Maryland.ORCID 0000-0001-8553-7605
Anna GongJohns Hopkins School of Medicine (A.G., D.B., S.M.), Baltimore, Maryland.
David BotrosJohns Hopkins School of Medicine (A.G., D.B., S.M.), Baltimore, Maryland.ORCID 0000-0002-2517-9583
Sasicha ManupipatpongJohns Hopkins School of Medicine (A.G., D.B., S.M.), Baltimore, Maryland.
Ferdinand K HuiRussell H. Morgan Department of Radiology and Radiological Science (R.E., F.K.H.), The Johns Hopkins Hospital, Baltimore, Maryland.ORCID 0000-0003-3759-7886
Majid KhanNon-Vascular Interventional Neuroradiology (M.K.), Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.ORCID 0000-0002-3807-1387
Johns Hopkins University · USJohns Hopkins Hospital · USMassachusetts General Hospital · USQueen's Medical Center · USThomas Jefferson University Hospital · US

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

background and purposeVertebral compression fracture represents a major health burden for the aging populations globally. However, limited studies exist on the relative efficacy and safety of surgical interventions for vertebral compression fracture. Here, we aim to compare clinical and patient-reported outcomes following vertebral augmentation using balloon kyphoplasty, vertebroplasty, and SpineJack vertebral implant. MATERIALS AND

methodsAn institutional review board-approved, retrospective, multi-institutional review of patients undergoing vertebral augmentation with kyphoplasty, vertebroplasty, and/or a SpineJack vertebral implant was performed between 2018 and 2021. Primary outcomes included pre- and postprocedural pain ratings and vertebral body height restoration. The secondary outcome was a change in the local kyphotic angle. The Kruskal-Wallis test was used to compare outcomes across 3 treatment options. Complications were reviewed during and 30-90 days after the procedure.

resultsVertebral augmentation of 344 vertebral compression fracture levels was performed during the study period. Sixty-seven patients had 79 kyphoplasty procedures (55% women; mean age, 64.2 [SD, 12.3] years). Seventy-four patients underwent a mean of 84 vertebroplasty procedures (51% women; mean age, 63.5 [SD, 12.8] years), and 61 patients had a mean of 67 SpineJack vertebral implant procedures (57.4% women; mean age, 68.3 [SD, 10.6] years). Following kyphoplasty, vertebroplasty, and SpineJack vertebral implant, pain scores improved significantly (

conclusionsThe SpineJack vertebral implant showed equivalent pain improvement compared with vertebroplasty and kyphoplasty, but it had superior vertebral body height restoration and local kyphotic angle improvement. This study supports the SpineJack vertebral implant as a safe and effective alternative (adjunct) for vertebral augmentation, especially in patients with moderate-to-severe vertebral compression fractures for greater improvement in vertebral body height restoration.

Indexed as

Fractures, CompressionKyphoplastyOsteoporotic FracturesSpinal FracturesVertebroplastyAgedBone CementsFemaleHumansMaleMiddle AgedPainRetrospective StudiesTreatment OutcomeBone Cements

Identifiers

PMID37918938
PMCPMC10631528
OpenAlexW4388216118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.