Evidence map›Paper›PMID 37918916›Full record

ArticleSexually transmitted infections2024

Implementation preferences for the management of sexually transmitted infections in the South African health system: a discrete choice experiment.

Collins Iwuji, Catherine E Martin, Diantha Pillay, Patience Shamu, Susan Nzenze, Mercy Murire, Laura Ashleigh Cox, Alec Miners, Carrie Llewellyn, Saiqa Mullick

Open access · hybridAbstract read
In one paragraph

Article in Sexually transmitted infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Collins IwujiDepartment of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton, UK c.iwuji@bsms.ac.uk.ORCID 0000-0003-2045-1717
Catherine E MartinDepartment of Implementation Science, Wits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Diantha PillayDepartment of Implementation Science, Wits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Patience ShamuDepartment of Implementation Science, Wits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Susan NzenzeDepartment of Implementation Science, Wits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Mercy MurireDepartment of Implementation Science, Wits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Laura Ashleigh CoxDepartment of Implementation Science, Wits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Alec MinersFaculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Carrie LlewellynPrimary Care and Public Health, Brighton and Sussex Medical School, University of Sussex, Brighton, UK.ORCID 0000-0002-9107-8473
Saiqa MullickDepartment of Implementation Science, Wits Reproductive Health and HIV Institute, Johannesburg, South Africa.
Perinatal HIV Research Unit · ZABrighton and Sussex Medical School · GBLondon School of Hygiene & Tropical Medicine · GB

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
NIH HHS P51 OD011133Wellcome Trust
6 · The paper itself

Abstract

objectivesDespite strengthening HIV prevention with the introduction of pre-exposure prophylaxis (PrEP), STI services have remained relatively unchanged and the standard of care remains syndromic management. We used a discrete choice experiment to investigate service users' preferences for the diagnosis and treatment of STIs in South Africa.

methodsBetween 1 March 2021 and 20 April 2021, a cross-sectional online questionnaire hosted on REDCap was administered through access links sent to WhatsApp support groups for HIV PrEP users and attendees of two primary healthcare clinics and two mobile facilities in the Eastern Cape and Gauteng provinces aged between 18 and 49 years. Participants either self-completed the questionnaire or received support from a research assistant. We used a conditional logit model for the initial analysis and latent class model (LCM) to establish class memberships, with results displayed as ORs and probabilities.

resultsWe enrolled 496 individuals; the majority were female (69%) and <30 years (74%). The LCM showed two distinct groups. The first group, comprising 68% of the participants, showed a strong preference for self-sampling compared with no sampling (OR 2.16, 95% CI 1.62 to 2.88). A clinic follow-up appointment for treatment was less preferable to same-day treatment (OR 0.78, 95% CI 0.63 to 0.95). Contact slip from index patient (OR 0.86, 95% CI 0.76 to 0.96) and healthcare professional (HCP)-initiated partner notification (OR 0.63, 95% CI 0.55 to 0.73) were both less preferable than expedited partner treatment (EPT). The second group included 32% of participants with a lower preference for self-sampling compared with no sampling (OR 0.65, 95% CI 0.41 to 1.04). There was no treatment option that was significantly different from the others; however, there was a strong preference for HCP-initiated partner notification to EPT (OR 1.53, 95% CI 1.10 to 2.12).

conclusionsOur results suggest that service users preferred STI testing prior to treatment, with the majority preferring self-taken samples and receiving aetiology-based treatment on the same day.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexually Transmitted DiseasesAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedSouth AfricaYoung AdultBacterial InfectionsHIV pre-exposure prophylaxisPARTNER NOTIFICATIONSEXUAL HEALTHSYNDROMIC MANAGEMENT

Identifiers

PMID37918916
PMCPMC10850665
OpenAlexW4388216307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.