Evidence map›Paper›PMID 37918865›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Imaging Agents for PET of Inflammatory Bowel Disease: A Review.

Farzaneh Rezazadeh, Aidan P Kilcline, Nerissa T Viola

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Regional and Sex-Dependent Immune Profiling Across the Colon in A Mouse Model of Ulcerative Colitis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. A NovelPharmaceutics · 2025
    Article
  4. Article
  5. CD45-targeted PET enables the visualization of inflammatory conditions.American journal of nuclear medicine and molecular imaging · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Farzaneh RezazadehDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan.
Aidan P KilclineDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan.
Nerissa T ViolaDepartment of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan violan@karmanos.org.
The Barbara Ann Karmanos Cancer Institute · USWayne State University · US

Funding

Delineating Functional Immunity via Image-Guided PETR37CA220482 · NCI · WAYNE STATE UNIVERSITY · PI GIBSON, HEATHER MARIE, VIOLA, NERISSA THERESE · 2018 to 2024
$3.9M
NCI NIH HHS R37 CA220482
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), which encompasses ulcerative colitis and Crohn disease, is a chronic inflammatory disorder resulting from an aberrant immune response, though its exact cause is unknown. The current mainstay standard of care for the diagnosis and surveillance of IBD is endoscopy. However, this methodology is invasive and images only superficial tissue structures, revealing very little about the molecular drivers of inflammation. Accordingly, there is an unmet need for noninvasive imaging tools that provide reliable and quantitative visualization of intestinal inflammation with high spatial and molecular specificity. In recent years, several PET agents for imaging IBD have been reported. Such agents allow noninvasive visualization and quantification of dynamic molecular inflammatory processes in vivo. This review focuses on recent advancements in the development of PET tracers for imaging biomarkers of interest in IBD pathogenesis, such as cell-surface molecules that are overexpressed on immune cells and cytokines that perpetuate inflammatory signaling.

Indexed as

Colitis, UlcerativeCrohn DiseaseInflammatory Bowel DiseasesHumansInflammationPositron-Emission Tomographyinflammationinflammatory bowel diseasenoninvasive imagingPET

Identifiers

PMID37918865
PMCPMC10690123
OpenAlexW4388210633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.