Evidence map›Paper›PMID 37918861›Full record

ArticleGlobal spine journal2025

Comparison of 5-Item and 11-Item Modified Frailty Index as Predictors of Functional Independence in Patients With Spinal Cord Injury.

Nikolaos Mouchtouris, Trevor Luck, Katherine Locke, Kevin Hines, Daniel Franco, Clifford Yudkoff, Ahilan Sivaganesan, Joshua Heller, Srinivas Prasad, James Harrop and 1 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Nikolaos MouchtourisDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.ORCID 0000-0001-9495-9391
Trevor LuckDepartment of Neurosurgery, Drexel University College of Medicine, Philadelphia, PA, USA.
Katherine LockeDepartment of Neurosurgery, Drexel University College of Medicine, Philadelphia, PA, USA.
Kevin HinesDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.ORCID 0000-0003-1700-174X
Daniel FrancoDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.
Clifford YudkoffDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.ORCID 0000-0003-0432-5315
Ahilan SivaganesanDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.
Joshua HellerDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.
Srinivas PrasadDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.
James HarropDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.
Jack JalloDepartment of Neurosurgery, Thomas Jefferson Universityand Jefferson Hospital for Neuroscience, Philadelphia, PA, USA.
Thomas Jefferson University · USDrexel University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective Cohort Study.

introductionThe 11-item modified Frailty index (mFI-11) by the ACS-NSQIP database was used to predict which patients are high risk for complications and inpatient mortality. ACS-NSQIP now has switched to the 5-item MFI. However, there are no studies on how these frailty indices fare against each other and their prognostic value of functional independence in patients with spinal cord injury (SCI).

objectiveTo compare the mFI-5 and mFI-11 in order to standardize frailty assessment in the SCI population.

methodsRetrospective analysis of 272,174 patients with SCI from 2010 to 2020 from the Pennsylvania Trauma Systems Foundation (PTSF) registry. Multivariable logistic regression was used to determine the predictive value of mFI for functional independence as determined by locomotion and transfer mobility.

resultsA total of 1907 patients were included with a mean age of 46.9 ± 15.1 years. The 3 most common MFI factors were hypertension (32.2%), diabetes mellitus (13.7%) and chronic obstructive pulmonary disease (8.5%). Multivariable logistic regression analyses using MFI-5 and MFI-11 showed that a higher frailty score in MFI-5 (OR 1.375,

conclusionThe new MFI-5 is equivalent to its predecessor, the MFI-11, and predictive of functional outcomes in patients with SCI. MFI-5 can serve as the preferred frailty index at the point of care and in research contexts.

Indexed as

frailty indexoutcomespredictors of functional independencespinal cord injury

Identifiers

PMID37918861
PMCPMC11877504
OpenAlexW4388248414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.