Evidence map›Paper›PMID 37917718›Full record

ArticlePLoS computational biology2023

Interaction between decision-making and motor learning when selecting reach targets in the presence of bias and noise.

Tianyao Zhu, Jason P Gallivan, Daniel M Wolpert, J Randall Flanagan

Abstract read
In one paragraph

Article in PLoS computational biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tianyao ZhuCentre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0003-4031-439X
Jason P GallivanCentre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0002-7362-109X
Daniel M WolpertZuckerman Mind Brain Behavior Institute, Columbia University, New York, New York.
J Randall FlanaganCentre for Neuroscience Studies, Queen's University, Kingston, Ontario, Canada.

Funding

Computations in Human Motor LearningR01NS117699 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WOLPERT, DANIEL · 2021 to 2025
$2.5M
NINDS NIH HHS R01 NS117699
6 · The paper itself

Abstract

Motor errors can have both bias and noise components. Bias can be compensated for by adaptation and, in tasks in which the magnitude of noise varies across the environment, noise can be reduced by identifying and then acting in less noisy regions of the environment. Here we examine how these two processes interact when participants reach under a combination of an externally imposed visuomotor bias and noise. In a center-out reaching task, participants experienced noise (zero-mean random visuomotor rotations) that was target-direction dependent with a standard deviation that increased linearly from a least-noisy direction. They also experienced a constant bias, a visuomotor rotation that varied (across groups) from 0 to 40 degrees. Critically, on each trial, participants could select one of three targets to reach to, thereby allowing them to potentially select targets close to the least-noisy direction. The group who experienced no bias (0 degrees) quickly learned to select targets close to the least-noisy direction. However, groups who experienced a bias often failed to identify the least-noisy direction, even though they did partially adapt to the bias. When noise was introduced after participants experienced and adapted to a 40 degrees bias (without noise) in all directions, they exhibited an improved ability to find the least-noisy direction. We developed two models-one for reach adaptation and one for target selection-that could explain participants' adaptation and target-selection behavior. Our data and simulations indicate that there is a trade-off between adaptation and selection. Specifically, because bias learning is local, participants can improve performance, through adaptation, by always selecting targets that are closest to a chosen direction. However, this comes at the expense of improving performance, through selection, by reaching toward targets in different directions to find the least-noisy direction.

Indexed as

Psychomotor PerformanceVisual PerceptionAdaptation, PhysiologicalBiasHumansLearningMovementNoise

Identifiers

PMID37917718
PMCPMC10703408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.