Evidence map›Paper›PMID 37917715›Full record

SynthesisPloS one2023

Physical exercise and its effects on people with Parkinson's disease: Umbrella review.

Cristiano Padilha, Renan Souza, Fernando Schorr Grossl, Ana Paula Maihack Gauer, Clodoaldo Antônio de Sá, Sinval Adalberto Rodrigues-Junior

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristiano PadilhaHealth Sciences Post-Graduate Program, Universidade Comunitária da Região de Chapecó-Unochapecó, Chapecó, Santa Catarina, Brazil.
Renan SouzaHealth Sciences Post-Graduate Program, Universidade Comunitária da Região de Chapecó-Unochapecó, Chapecó, Santa Catarina, Brazil.
Fernando Schorr GrosslHealth Sciences Post-Graduate Program, Universidade Comunitária da Região de Chapecó-Unochapecó, Chapecó, Santa Catarina, Brazil.
Ana Paula Maihack GauerHealth Sciences Post-Graduate Program, Universidade Comunitária da Região de Chapecó-Unochapecó, Chapecó, Santa Catarina, Brazil.
Clodoaldo Antônio de SáHealth Sciences Post-Graduate Program, Universidade Comunitária da Região de Chapecó-Unochapecó, Chapecó, Santa Catarina, Brazil.
Sinval Adalberto Rodrigues-JuniorHealth Sciences Post-Graduate Program, Universidade Comunitária da Região de Chapecó-Unochapecó, Chapecó, Santa Catarina, Brazil.ORCID 0000-0002-4475-1725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionParkinson's disease is neurodegenerative, complex and progressive, manifesting in a slow and irreversible way. Physical exercise has been proposed as therapeutic alternative to people with Parkinson´s disease.

objectiveTo synthesize knowledge about the effects of physical exercise on people with Parkinson´s Disease as presented by published systematic reviews.

methodsNine electronic databases and two grey literature databases were searched for systematic reviews reporting the effects of physical exercises on people with Parkinson´s Disease. Searches involved a two-phase process, by, at least, two independent reviewers. Methodological quality of the included systematic reviews was assessed using AMSTAR-2.

resultsFrom 2,122 systematic reviews, 139 were included. Motor outcomes were assessed in 91% of the studies, with balance being the most studied. Non-motor outcomes were assessed in 68% of the studies, with emphasis on quality of life. Physical exercises were classified into five categories: aerobic exercises, strength, combined, sensorimotor activities and other activity protocols. Findings of the systematic reviews suggest that all exercise categories can be prescribed to improve balance and mobility, while combined exercises, strength, and specific activities improve both motor and non-motor outcomes, and aerobic exercise and sensorimotor activities improve motor outcomes.

conclusionCurrent evidence from systematic reviews suggests that physical exercises impacts both motor and non-motor outcomes in people with Parkinson´s Disease. Limits in evidence provided by the systematic reviews were related to methodological issues and to the description of the interventions and must be considered to improve decision-making and clinical application.

Indexed as

Parkinson DiseaseExerciseExercise TherapyHumansQuality of LifeSystematic Reviews as Topic

Identifiers

PMID37917715
PMCPMC10621990

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.