Evidence map›Paper›PMID 37917661›Full record

ArticleGlobal spine journal2024

The Frequency of Symptoms in Patients With a Diagnosis of Degenerative Cervical Myelopathy: Results of a Scoping Review.

Zhilin Jiang, Benjamin Davies, Carl Zipser, Konstantinos Margetis, Allan Martin, Stavros Matsoukas, Freschta Zipser-Mohammadzada, Najmeh Kheram, Andrea Boraschi, Elina Zakin and 13 more

Open access · goldAbstract readScoping Review
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  9. Understanding degenerative cervical myelopathy in musculoskeletal practice.The Journal of manual & manipulative therapy · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 13 institutions in 5 countries.

Zhilin JiangKing's College Hospital, NHS Foundation Trust, London, UK.
Benjamin DaviesUniversity of Cambridge, Cambridge, UK.ORCID 0000-0003-0591-5069
Carl ZipserSpinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland.
Konstantinos MargetisDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-3715-8093
Allan MartinDepartment of Neurosurgery, University of California Davis, Davis, CA, USA.
Stavros MatsoukasDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Freschta Zipser-MohammadzadaSpinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland.
Najmeh KheramSpinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland.
Andrea BoraschiThe Interface Group, Institute of Physiology, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-2908-5234
Elina ZakinDepartment of Neurology, New York UniversityLangone, New York, NY, USA.
Oke Righteous ObadaserayeDepartment of Surgery, Asaba Specialist Hospital, Asaba, Nigeria.ORCID 0000-0001-8018-6076
Michael G FehlingsDivision of Neurosurgery and Spinal Program, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-5722-6364
Jamie WilsonUniversity of Nebraska Medical Center, Omaha, NE, USA.
Ratko YuracProfessor of Orthopedics and Traumatology, University del Desarrollo, Clinica Alemana de Santiago, Santiago, Chile.ORCID 0000-0003-3603-6294
Chad E CookDuke University Medical Center, Durham, NC, USA.
Jamie MilliganDepartment of Family Medicine, McMaster University, Hamilton, ON, USA.
Julia TabrahHounslow and Richmond Community Healthcare, London, UK.
Shirley WiddopMyelopathy.org, Cambridge, UK.
Lianne WoodNottingham University Hospital, Nottingham, UK.
Elizabeth A RobertsMyelopathy.org, Cambridge, UK.ORCID 0000-0003-2738-4203
Tanzil RujeedawaUniversity of Cambridge, Cambridge, UK.ORCID 0000-0002-7089-1684
Lindsay TetreaultDepartment of Neurology, New York UniversityLangone, New York, NY, USA.
AO Spine RECODE-DCM Diagnostic Criteria Incubator
Icahn School of Medicine at Mount Sinai · USMyeloma UK · GBNew York University · USUniversitätsklinik Balgrist · CHUniversity of Cambridge · GBUniversity of Zurich · CHDuke Medical Center · USHounslow and Richmond Community Healthcare NHS Trust · GBKing's College Hospital NHS Foundation Trust · GBUniversidad del Desarrollo · CLUniversity of California, Davis · USUniversity of Nebraska Medical Center · USUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designDelayed diagnosis of degenerative cervical myelopathy (DCM) is associated with reduced quality of life and greater disability. Developing diagnostic criteria for DCM has been identified as a top research priority.

objectivesThis scoping review aims to address the following questions: What is the diagnostic accuracy and frequency of clinical symptoms in patients with DCM?

methodsA scoping review was conducted using a database of all primary DCM studies published between 2005 and 2020. Studies were included if they (i) assessed the diagnostic accuracy of a symptom using an appropriate control group or (ii) reported the frequency of a symptom in a cohort of DCM patients.

resultsThis review identified three studies that discussed the diagnostic accuracy of various symptoms and included a control group. An additional 58 reported on the frequency of symptoms in a cohort of patients with DCM. The most frequent and sensitive symptoms in DCM include unspecified paresthesias (86%), hand numbness (82%) and hand paresthesias (79%). Neck and/or shoulder pain was present in 51% of patients with DCM, whereas a minority had back (19%) or lower extremity pain (10%). Bladder dysfunction was uncommon (38%) although more frequent than bowel (23%) and sexual impairment (4%). Gait impairment is also commonly seen in patients with DCM (72%).

conclusionPatients with DCM present with many different symptoms, most commonly sensorimotor impairment of the upper extremities, pain, bladder dysfunction and gait disturbance. If patients present with a combination of these symptoms, further neuroimaging is indicated to confirm the diagnosis of DCM.

Indexed as

cervicaldegenerative disc diseasemyelopathy

Identifiers

PMID37917661
PMCPMC11289544
OpenAlexW4388215098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.