Evidence map›Paper›PMID 37917419›Full record

ArticleDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2024

Towards greater impact in health technology assessment: System dynamic approach for new and emerging technologies in Iran.

Zahra Goudarzi, Milad Ahmadi Marzaleh, Shekoufeh Nikfar, Abbas Kebriaeezadeh, Reza Yousefi Zenouz, Akbar Abdollahiasl, Mojtaba Nouhi

Open access · greenAbstract read
In one paragraph

Article in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zahra GoudarziFaculty of Medical Information and Management, Health Human Resources Research Centre, School of Health Management and Information Sciences, Shiraz University of Medical Sciences, Qasr Al-Dasht St., 27 Alley, Shiraz, 7133654361, Iran.ORCID http://orcid.org/0000-0002-7096-5276
Milad Ahmadi MarzalehDepartment of Health in Disasters and Emergencies, Faculty of Medical Information and Management, School of Health Management and Information Sciences, Shiraz University of Medical Sciences, Qasr Al-Dasht St., 27 Alley, Shiraz, 7133654361, Iran.ORCID http://orcid.org/0000-0003-1743-0093
Shekoufeh NikfarDepartment of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Enghelab Square,16 Azar St., Tehran, 1417614411, Iran.ORCID http://orcid.org/0000-0002-5206-6197
Abbas KebriaeezadehDepartment of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Enghelab Square,16 Azar St., Tehran, 1417614411, Iran.ORCID http://orcid.org/0000-0003-3872-2474
Reza Yousefi ZenouzDepartment of Operations and Information Technology Management, Faculty of Management, Kharazmi University, Tehran Between Shahid Qorani and Ostad Nejatollahi, Somia St, No 242, Tehran, 159996415, Iran.ORCID http://orcid.org/0000-0001-8188-1126
Akbar AbdollahiaslDepartment of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Enghelab Square,16 Azar St., Tehran, 1417614411, Iran. abdollahiasl@tums.ac.ir.ORCID http://orcid.org/0000-0002-3686-4770
Mojtaba NouhiNational Institute for Health Research, Tehran University of Medical Sciences, Keshahvarz Blvd, Vasal Shirazi Street, Bozorgmehr East Street, Number 70, Tehran, 62921000, Iran.ORCID http://orcid.org/0000-0002-4445-1140
Tehran University of Medical Sciences · IRShiraz University of Medical Sciences · IRKharazmi University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAs classical health technology assessment models fail to predict the complexities of related impacts, the application of modeling techniques such as systems dynamics simulation (SD) is essential. This study aimed to develop an SD model to predict the outcomes of access to a new medicine in Iran.

methodsThis study extracted the important and influential variables in providing access to new pharmaceutical technologies by comprehensively reviewing previous research and combining the technical knowledge of experts in this field. The variables were incorporated into the systems thinking framework and modeled using dynamic systems tools, followed by simulation and testing in VENSIM. The model was piloted for deferoxamine and deferasirox in thalassemia. Various tests were used to evaluate the validity and reliability of the model. The model was designed for a ten-year horizon (2018-2028) for medicines selected as the pilot.

resultsThe variables extracted from the panel of experts encompassed the primary and short-term impacts of access to newly emerged medicine and long-term impacts regarding the economy, health, and society. After modeling, the leverage points presented for the problem with the greatest impact or effectiveness in access to new medicine included the policy determining the amount of medicine supply, the import and production of medicine, the prevalence and incidence of disease, insurance coverage, and treatment adherence.

conclusionThe SD models allow the researchers to evaluate the efficiency and health outcomes of a new pharmaceutical more precisely in the health system in Iran.

Indexed as

Technology Assessment, BiomedicalHumansIranDynamic modelingHealth technology assessmentHorizon scanningNew medicine

Identifiers

PMID37917419
PMCPMC11087392
OpenAlexW4388232363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.