Evidence map›Paper›PMID 37917395›Full record

ArticleInfection2024

Viral lumbosacral radiculitis (Elsberg syndrome) in Denmark.

Pelle Trier Petersen, Jacob Bodilsen, Micha Phill Grønholm Jepsen, Lykke Larsen, Merete Storgaard, Birgitte Rønde Hansen, Hans Rudolf Lüttichau, Jannik Helweg-Larsen, Lothar Wiese, Christian Østergaard Andersen and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Infection, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Pelle Trier PetersenDepartment of Pulmonary and Infectious Diseases, Nordsjællands Hospital, Dyrehavevej 29, 3400, Hillerød, Denmark. pelle.trier.petersen.01@regionh.dk.
Jacob BodilsenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.
Micha Phill Grønholm JepsenDepartment of Pulmonary and Infectious Diseases, Nordsjællands Hospital, Dyrehavevej 29, 3400, Hillerød, Denmark.
Lykke LarsenDepartment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Merete StorgaardDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Birgitte Rønde HansenDepartment of Infectious Diseases, Hvidovre Hospital, Hvidovre, Denmark.
Hans Rudolf LüttichauDepartment of Infectious Diseases, Herlev Hospital, Herlev, Denmark.
Jannik Helweg-LarsenDepartment of Infectious Diseases, Rigshospitalet, Copenhagen, Denmark.
Lothar WieseDepartment of Medicine, Zealand University Hospital, Roskilde, Denmark.
Christian Østergaard AndersenDepartment of Clinical Microbiology, Hvidovre Hospital, Hvidovre, Denmark.
Henrik NielsenDepartment of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark.
Christian Thomas BrandtDepartment of Medicine, Zealand University Hospital, Roskilde, Denmark.
Danish Study Group of Infections of the Brain (DASGIB)
Aalborg University · DKHvidovre Hospital · DKZealand University Hospital · DKAarhus University Hospital · DKHerlev Hospital · DKNordsjællands Hospital · DKOdense University Hospital · DKRigshospitalet · DKUniversity of Copenhagen · DK

Funding

Helen Rudes Fond, Denmark 60988Helsefonden, Denmark 21-B-0437Minister Erna Hamiltons Legat for Videnskab og Kunst, Denmark 24-2022
6 · The paper itself

Abstract

purposeTo describe clinical features and outcomes of viral lumbosacral radiculitis (Elsberg syndrome).

methodsNationwide population-based cohort study of all adults hospitalised for viral lumbosacral radiculitis at departments of infectious diseases in Denmark from 2015 to 2020.

resultsTwenty-eight patients with viral lumbosacral radiculitis were included (mean annual incidence: 1.2/1,000,000 adults). The median age was 35 years (IQR 27-43), and 22/28 (79%) were female. All patients had urinary retention, with 17/28 (61%) needing a catheter. On admission, at least one sign or symptom of meningitis (headache, neck stiffness, photophobia/hyperacusis) was present in 18/22 (82%). Concurrent genital herpetic lesions were present in 11/24 (46%). The median cerebrospinal fluid leukocyte count was 153 cells/µL (IQR 31-514). Magnetic resonance imaging showed radiculitis/myelitis in 5/19 (26%). The microbiological diagnosis was herpes simplex virus type 2 in 19/28 (68%), varicella-zoster virus in 2/28 (7%), and unidentified in 7/28 (25%). Aciclovir/valaciclovir was administered in 27/28 (96%). At 30 days after discharge, 3/27 (11%) had persistent urinary retention with need of catheter. At 180 days after discharge, moderate disabilities (Glasgow Outcome Scale score of 4) were observed in 5/25 (20%).

conclusionsUrinary retention resolved within weeks in most patients with viral lumbosacral radiculitis, but moderate disabilities according to the Glasgow Outcome Scale were common at the end of follow-up.

Indexed as

RadiculopathyAdultCohort StudiesDenmarkFemaleHerpesvirus 2, HumanHerpesvirus 3, HumanHerpes ZosterHumansLumbosacral RegionMaleMiddle AgedUrinary RetentionAciclovirAseptic meningitisHerpesviridaeMyelitisUrinary retentionViral meningitis

Identifiers

PMID37917395
PMCPMC11143033
OpenAlexW4388218192

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.