Evidence map›Paper›PMID 37917392›Full record

ArticleObesity surgery2023

Long-Term Outcomes of Bariatric Surgery in Patients on Chronic Anticoagulation.

Kamal Abi Mosleh, Amanda Belluzzi, Marita Salame, Michael L Kendrick, Barham K Abu Dayyeh, Travis J McKenzie, Omar M Ghanem

Abstract read
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Article in Obesity surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kamal Abi MoslehDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Amanda BelluzziDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Marita SalameDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Michael L KendrickDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Barham K Abu DayyehDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Travis J McKenzieDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Omar M GhanemDepartment of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA. ghanem.omar@mayo.edu.ORCID 0000-0003-2459-2621
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApproximately 3% of patients undergoing metabolic and bariatric surgery (MBS) are receiving chronic anticoagulation therapy (CAT) prior to operation. The management of these patients is complex, as it involves balancing the potential risk of thrombosis against that of bleeding. Our primary objective is to assess the long-term bleeding risk in patients undergoing MBS. We also aim to observe the trends in anticoagulant dosing after MBS.

methodsA single-center retrospective review of patients who underwent either primary Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) with preoperative CAT between 2008 and 2022 was performed. Data on baseline demographics, indication for anticoagulation, type of CAT, and dosing were collected. Events of bleeding and the CAT at event were subsequently evaluated.

resultsA total of 132 patients (82 RYGB and 50 SG) initially on CAT were identified, with atrial fibrillation being the most common indication. Incidence of long-term bleeding was significantly higher in the RYGB group (18.3%) compared to the SG group (4%) (p = 0.017) over a total of 5.2 ± 3.8 years. Bleeding marginal ulcer (MU) was the most common cause of bleeding in the RYGB group (13.4%). 84.2% of all bleeding events occurred in patients on chronic Warfarin therapy.

conclusionLong-term CAT is associated with an increased risk of bleeding in RYGB patients, particularly MU bleeds. Patients on CAT seeking MBS should be counseled regarding this risk and potential implications. Direct-acting oral anticoagulants offer promise as an alternative to Warfarin in these patients; further research is necessary to better understand their safety.

Indexed as

Bariatric SurgeryGastric BypassObesity, MorbidAnticoagulantsGastrectomyHemorrhageHumansRetrospective StudiesTreatment OutcomeWarfarinAnticoagulantsWarfarinChronic anticoagulation therapyGastric bypassGastrointestinal bleedingSleeve gastrectomy

Identifiers

PMID37917392
OpenAlexW4388219417

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.