Evidence map›Paper›PMID 37917387›Full record

ReviewCurrent HIV/AIDS reports2023

Pharmacological and Behavioral Interventions to Mitigate Premature Aging in Patients with HIV.

Roxane Rohani, Jacob Malakismail, Emmanuel Njoku

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current HIV/AIDS reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Association of Step Count with Cardiorespiratory Fitness: Results from the Virtual 2-Minute Step Test.Archives of rehabilitation research and clinical translation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Roxane RohaniDiscipline of Cellular and Molecular Pharmacology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road BSB 3.266, North Chicago, IL, USA. roxane.rohani@rosalindfranklin.edu.
Jacob MalakismailChicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA.
Emmanuel NjokuSection of Infectious Disease, Captain James A. Lovell Federal Health Care Center, North Chicago, IL, USA.
Rosalind Franklin University of Medicine and Science · USCaptain James A. Lovell Federal Health Care Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewWe sought to review pharmacological and behavioral interventions that have been publicly presented, published, or are currently ongoing to prevent or mitigate the effect of premature HIV-associated comorbidities. RECENT

findingsMultiple studies have been conducted in hopes of finding an effective intervention. While the choice of antiretroviral regimen influences recovery of immune function, several drugs used as adjunct treatments have proven effective to mitigate premature aging. Additionally, few behavioral interventions have exhibited some efficacy. Statins, angiotensin-receptor blockers, and anti-hyperglycemic agents as well as optimal adherence, exercise, and intermittent fasting among others have had beneficial impact on markers of immune activation and levels of inflammatory biomarkers. However, several investigations had inconclusive outcomes so further studies with larger sample sizes are warranted.

Indexed as

Aging, PrematureHIV InfectionsAgingAnti-Retroviral AgentsBehavior TherapyBiomarkersHumansInflammationAnti-Retroviral AgentsBiomarkersChronic inflammationEarly aging preventionHIV-associated comorbiditiesImmunosenescenceInflammagingTherapeutic interventions

Identifiers

PMID37917387
OpenAlexW4388228772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.