Evidence map›Paper›PMID 37917247›Full record

Observational studyClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2024

Sexual dysfunction in patients with cancer, a challenge in oncology practice: results of the CLARIFY project.

Aylen Vanessa Ospina-Serrano, Constanza Maximiano, Blanca Cantos, Maria Torrente, Miriam Mendez, Juan Cristobal Sanchez, Virginia Calvo, Ana Collazo-Lorduy, Mariola Blanco, Beatriz Nuñez and 5 more

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06018376 (Characteristics of Sexual Dysfunction in Patients With Lung Cancer), which is not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06018376 completednot on this map

Characteristics of Sexual Dysfunction in Patients With Lung Cancer

TypeobservationalSponsorFundación GECPRan2023 to 2024Enrolled553ConditionsLung Cancer, Sexual DysfunctionArmsSystemic oncological treatment
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Sexual health of patients with lung cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Nurses' attitudes toward addressing sexual health in their professional practice within cancer care: a Danish cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  8. Article
  9. Article
  10. Access to systemic treatment of non-melanoma skin cancer in Spain: a survey analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  11. Access to melanoma drugs in Spain: a cross-sectional survey.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
  12. Article
  13. Approach to lubricant use for sexual activity.Canadian family physician Medecin de famille canadien
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Aylen Vanessa Ospina-SerranoInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España. avospina@hotmail.com.ORCID http://orcid.org/0000-0002-4992-4306
Constanza MaximianoInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0002-4051-3965
Blanca CantosInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0003-2105-1213
Maria TorrenteInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0001-8791-7660
Miriam MendezInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0002-1579-5809
Juan Cristobal SanchezInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0001-6442-1574
Virginia CalvoInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0002-3503-4847
Ana Collazo-LorduyInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0003-4163-3392
Mariola BlancoInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0001-9601-9301
Beatriz NuñezInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0003-2639-5162
Ivan TrianaHospital Universitario Fundación Santa Fe de Bogotá, Bogota, Colombia.ORCID http://orcid.org/0000-0002-8349-5576
Consuelo ParejoInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0002-7957-7149
Paula MartinezInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0001-9383-9662
Narjust DumaDana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-7814-1773
Mariano Provencio-PullaInstituto Investigación Sanitaria Puerta de Hierro-Segovia de Arana (IDIPHISA), Hospital Universitario Puerta de Hierro-Majadahonda, C/Manuel de Falla, 1, 28222, Madrid, Majadahonda, España.ORCID http://orcid.org/0000-0001-6315-7919
Hospital Universitario Puerta de Hierro Majadahonda · ESFundación Santa Fe de Bogotá · COHarvard University · US

Funding

HORIZON EUROPE European Institute of Innovation and Technology 875160.
6 · The paper itself

Abstract

backgroundSexual dysfunction (SD) associated with oncological treatment is a common and understudied disorder. Our aim was to characterize SD in a cohort of Spanish patients.

methodsAnalytic observational study in patients included in the CLARIFY H2020 project at the Hospital Universitario Puerta de Hierro. Clinical variables and validated measures of sexual function were collected from October 2020 to May 2022. Frequency and quality of sexual activity were assessed. Descriptive, trend associations, and logistic regression analyses were performed.

resultsA total of 383 patients were included: breast cancer 68.14% (261), lung cancer 26.37% (101), and lymphoma 5.50% (21). Mean age was 56.5 years (range 33-88). 19.58% (75) were men and 80.42% (308) were women. 69% and 31% of men and women, respectively, reported being sexually active. The absolute frequency of overall sexual dissatisfaction was 76% in women and 24% in men. Women with breast cancer were most likely to have severe sexual dysfunction. Those with early disease had resolved complaints after 5 years. In multinomial logistic regression, significant associations were found in women with metastatic breast cancer and severe disorders of arousal (p 0.000), lubrication (p 0.002), orgasm (p 0.000), as well as dissatisfaction with sexual performance (p 0.000) and global sexual dissatisfaction (p 0.000). Women with lung cancer have severe arousal dysfunction (p 0.016) and global sexual dissatisfaction (p 0.044).

conclusionsOur population has a high prevalence of SD, which supports the need to increase awareness of this disorder among the medical oncology team and the importance of including sexual health assessment in oncological patient follow-up.

Indexed as

Breast NeoplasmsLung NeoplasmsSexual Dysfunction, PhysiologicalAdultAgedAged, 80 and overEuropean PeopleFemaleHumansMaleMedical OncologyMiddle AgedSexual BehaviorSpainSurveys and QuestionnairesCancerCohort studiesLong survivorsOncological treatmentSexual dysfunction

Identifiers

PMID37917247
OpenAlexW4388230988

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.