Evidence map›Paper›PMID 37917031›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2023

PCR testing of traced contacts for SARS-CoV-2 in England, January to July 2021.

Toby Nonnenmacher, Niharika Dandamudi, Matthias Erwin Futschik, Sarah A Tunkel, Raghavendran Kulasegaran-Shylini, Nick Germanacos, Joanna Cole-Hamilton, Edward Blandford, Ashley Goddard, Joe Hillier and 3 more

Abstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Toby NonnenmacherUnited Kingdom Health Security Agency, London, United Kingdom.
Niharika DandamudiUnited Kingdom Health Security Agency, London, United Kingdom.
Matthias Erwin FutschikFaculty of Health, School of Biomedical Sciences, University of Plymouth, Plymouth, United Kingdom.
Sarah A TunkelUnited Kingdom Health Security Agency, London, United Kingdom.
Raghavendran Kulasegaran-ShyliniUnited Kingdom Health Security Agency, London, United Kingdom.
Nick GermanacosUnited Kingdom Health Security Agency, London, United Kingdom.
Joanna Cole-HamiltonUnited Kingdom Health Security Agency, London, United Kingdom.
Edward BlandfordUnited Kingdom Health Security Agency, London, United Kingdom.
Ashley GoddardUnited Kingdom Health Security Agency, London, United Kingdom.
Joe HillierUnited Kingdom Health Security Agency, London, United Kingdom.
Stephen FinerUnited Kingdom Health Security Agency, London, United Kingdom.
Susan HopkinsUnited Kingdom Health Security Agency, London, United Kingdom.
Tom FowlerWilliam Harvey Research Institute, Queen Mary University of London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundThe NHS Test and Trace (NHSTT) programme was established in May 2020 in England to deliver SARS-CoV-2 testing and contact tracing in order to identify infected individuals and reduce COVID-19 spread. To further control transmission, people identified as contacts were asked to self-isolate for 10 days and test only if they became symptomatic. From March 2021, eligibility criteria for PCR testing expanded to include asymptomatic contacts of confirmed cases.AimTo analyse testing patterns of contacts before and after the change in testing guidance in England to assess the impact on PCR testing behaviour with respect to symptom status and contact type.MethodsTesting and contact tracing data were extracted from the national data systems and linked. Subsequently, descriptive statistical analysis was applied to identify trends in testing behaviour.ResultsBetween 1 January and 31 July 2021, over 5 million contacts were identified and reached by contact tracers; 42.3% took a PCR test around the time they were traced. Overall positivity rate was 44.3% and consistently higher in symptomatic (60-70%) than asymptomatic (around 20%, March-June) contacts. The proportion of tests taken by asymptomatic contacts increased over time, especially after the change in testing guidance. No link was observed between uptake of PCR tests and vaccination coverage. Fully vaccinated contacts showed lower positivity (23.8%) than those with one dose (37.2%) or unvaccinated (51.0%).ConclusionAlmost 1 million asymptomatic contacts were tested for SARS-CoV-2, identifying 214,056 positive cases, demonstrating the value of offering PCR testing to this group.

Indexed as

COVID-19SARS-CoV-2COVID-19 TestingEnglandHumansPolymerase Chain Reactioncontact testingcontact tracingCOVID-19NHS Test and TracePCRSARS-CoV-2

Identifiers

PMID37917031
PMCPMC10623643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.