Evidence map›Paper›PMID 37917024›Full record

ArticleThe Journal of cell biology2023

Super-resolution microscopy: Insights into mitochondria-lysosome crosstalk in health and disease.

Eric D Leisten, Abby C Woods, Yvette C Wong

Abstract read
In one paragraph

Article in The Journal of cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Revisiting the role of Annexins in membrane trafficking.Cellular and molecular life sciences : CMLS · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eric D LeistenDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0009-0005-7469-6009
Abby C WoodsDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0009-0009-3538-0393
Yvette C WongDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0002-3188-4342

Funding

The dynamic architecture of living cells: Uncovering intra-organelle events at nanoscale levelsDP2GM146322 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WONG, YVETTE · 2021 to 2024
$2.4M
Molecular mechanisms underlying mitochondria-lysosome membrane contact sites in neuronal function and neurodegenerationR00NS109252 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WONG, YVETTE · 2020 to 2023
$883k
NIGMS NIH HHS DP2 GM146322NIGMS NIH HHS DP2GM146322NINDS NIH HHS R00 NS109252NINDS NIH HHS R00NS109252
6 · The paper itself

Abstract

Live super-resolution microscopy has allowed for new insights into recently identified mitochondria-lysosome contact sites, which mediate crosstalk between mitochondria and lysosomes, including co-regulation of Rab7 GTP hydrolysis and Drp1 GTP hydrolysis. Here, we highlight recent findings and future perspectives on this dynamic pathway and its roles in health and disease.

Indexed as

LysosomesMicroscopyMitochondriaDynaminsGuanosine TriphosphateMitochondrial Membranesrab7 GTP-Binding ProteinsDynaminsGuanosine Triphosphaterab7 GTP-Binding Proteins

Identifiers

PMID37917024
PMCPMC10621667

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.