Evidence map›Paper›PMID 37916911›Full record

ArticleeLife2023

Selection on plastic adherence leads to hyper-multicellular strains and incidental virulence in the budding yeast.

Luke I Ekdahl, Juliana A Salcedo, Matthew M Dungan, Despina V Mason, Dulguun Myagmarsuren, Helen A Murphy

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luke I Ekdahl *Department of Biology, College of William and Mary, Williamsburg, United States.
Juliana A Salcedo *Department of Biology, College of William and Mary, Williamsburg, United States.
Matthew M DunganDepartment of Biology, College of William and Mary, Williamsburg, United States.
Despina V MasonDepartment of Biology, College of William and Mary, Williamsburg, United States.
Dulguun MyagmarsurenDepartment of Biology, College of William and Mary, Williamsburg, United States.
Helen A MurphyDepartment of Biology, College of William and Mary, Williamsburg, United States.ORCID 0000-0002-4363-4543

Funding

The Evolution and Genetics of Fungal VirulenceR15GM152938 · NIGMS · COLLEGE OF WILLIAM AND MARY · PI MURPHY, HELEN ANNE · 2023 to 2023
$416k
The Evolution and Genetics of a Complex Fungal Virulence TraitR15GM122032 · NIGMS · COLLEGE OF WILLIAM AND MARY · PI MURPHY, HELEN ANNE · 2017 to 2017
$307k
NIGMS NIH HHS R15 GM122032NIGMS NIH HHS R15 GM152938NIH HHS R15-GM122032
6 · The paper itself

Abstract

Many disease-causing microbes are not obligate pathogens; rather, they are environmental microbes taking advantage of an ecological opportunity. The existence of microbes whose life cycle does not require a host and are not normally pathogenic, yet are well-suited to host exploitation, is an evolutionary puzzle. One hypothesis posits that selection in the environment may favor traits that incidentally lead to pathogenicity and virulence, or serve as pre-adaptations for survival in a host. An example of such a trait is surface adherence. To experimentally test the idea of 'accidental virulence', replicate populations of

Indexed as

SaccharomycetalesAnimalsLife Cycle StagesPhenotypeSaccharomyces cerevisiaeVirulenceadherencebiofilmevolutionary biologyexperimental evolutionFLO11infectious diseasemicrobiologyS. cerevisiaevirulencewax mothyeast

Identifiers

PMID37916911
PMCPMC10764007

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.