Evidence map›Paper›PMID 37916709›Full record

ArticleJournal of comparative effectiveness research2023

Cost-effectiveness of obinutuzumab plus bendamustine in Chinese patients with relapse and refractory follicular lymphoma.

Jun Ma, Donglu Zhao, Bihong Zhen, Yan Xia, Qianyi Gong, Wendong Chen

Open access · diamondAbstract read
In one paragraph

Article in Journal of comparative effectiveness research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jun MaHarbin Institute of Hematology & Oncology, Harbin, China.
Donglu ZhaoHarbin Institute of Hematology & Oncology, Harbin, China.
Bihong ZhenShanghai Roche Pharmaceuticals Ltd, Shanghai, China.
Yan XiaShanghai Roche Pharmaceuticals Ltd, Shanghai, China.
Qianyi GongChangsha Normin Health Technology Ltd, Changsha, China.
Wendong ChenChangsha Normin Health Technology Ltd, Changsha, China.
Harbin Institute of Petroleum · CNRoche (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A decision analytic model was constructed to assess the cost-effectiveness of obinutuzumab plus bendamustine followed by obinutuzumab maintenance therapy (O-B-O) in Chinese patients with relapsed and refractory follicular lymphoma (rrFL). O-B-O was associated with a dominant or more favorable cost-effectiveness than the conventional therapies. Survival outcomes, quality of life of progression-free survival, and subsequent treatment costs for progressive disease were the main drivers of the cost-effectiveness of O-B-O. The cost-effectiveness proportions of O-B-O relative to conventional therapies under the recommended cost-effectiveness threshold ranged from 61.0% to 99.9%. Thus, O-B-O was highly cost-effective for treating patients with rrFL in China compared with conventional therapies.

Indexed as

Antibodies, Monoclonal, HumanizedBendamustine HydrochlorideLymphoma, FollicularAntineoplastic Combined Chemotherapy ProtocolsCost-Benefit AnalysisEast Asian PeopleHumansNeoplasm Recurrence, LocalQuality of LifeAntibodies, Monoclonal, HumanizedBendamustine HydrochlorideobinutuzumabChinacost–effectivenesshealthcare payersobinutuzumabrelapsed and refractory follicular lymphoma

Identifiers

PMID37916709
PMCPMC10734320
OpenAlexW4388223089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.