Evidence map›Paper›PMID 37916286›Full record

ArticleAmerican journal of physiology. Renal physiology2024

Tubular dysfunction impairs renal excretion of pseudouridine in diabetic kidney disease.

Anna V Mathew, Pradeep Kayampilly, Jaeman Byun, Viji Nair, Farsad Afshinnia, Biaoxin Chai, Frank C Brosius, Matthias Kretzler, Subramaniam Pennathur

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Renal physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Alterations of Plasma Metabolites Associated with Sickle Cell Trait.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  4. Article
  5. Renal tubular (pro)renin receptor deletion exacerbates kidney injury inAmerican journal of physiology. Renal physiology · 2025
    Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Anna V MathewDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.
Pradeep KayampillyDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.
Jaeman ByunDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.
Viji NairDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.
Farsad AfshinniaDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-3051-3141
Biaoxin ChaiDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.
Frank C BrosiusDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0002-4244-8335
Matthias KretzlerDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-4064-0582
Subramaniam PennathurDivision of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-3628-6883
University of Michigan · USUniversity of Arizona · US

Funding

PUBLIC HEALTH DEMONSTRATIONP60DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MYERS, MARTIN G · 1985 to 2012
$26.5M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Martin G Myers · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Karen Eileen Peterson · 2010 to 2026
$20.3M
Integrated Systems Biology Approach to Diabetic Microvascular ComplicationsR24DK082841 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ABCOUWER, STEVEN F, BROSIUS, FRANK C · 2008 to 2020
$13.1M
University of Michigan O'Brien Kidney Translational Core CenterP30DK081943 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PENNATHUR, SUBRAMANIAM · 2008 to 2022
$12.9M
Statistics and Bioinformatics Core - WangU24DK097153 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURANT, CHARLES F · 2012 to 2017
$10.1M
University of Michigan O'Brien Kidney Translational Resource Center (MKTC)U54DK137314 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Subramaniam Pennathur · 2023 to 2026
$4.7M
Myeloperoxidase, Chronic Kidney Disease and AtherosclerosisK08HL130944 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MATHEW, ANNA VACHAPARAMPIL · 2016 to 2021
$893k
NHLBI NIH HHS K08 HL130944NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK081943NIDDK NIH HHS P30 DK089503NIDDK NIH HHS P60 DK020572NIDDK NIH HHS R24 DK082841NIDDK NIH HHS U24 DK097153NIDDK NIH HHS U54 DK137314
6 · The paper itself

Abstract

Plasma nucleosides-pseudouridine (PU) and

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesAnimalsGuanosineHumansKidneyMiceNucleosidesPseudouridineRenal EliminationGuanosineNucleosidesPseudouridinediabetic kidney diseasemetabolic flux analysisN2N2-dimethyl guanosinenucleosidepseudouridine

Identifiers

PMID37916286
PMCPMC11194048
OpenAlexW4388226842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.