Evidence map›Paper›PMID 37915985›Full record

ArticleFrontiers in pediatrics2023

Mycophenolate mofetil for autoimmune cytopenias in children: high rates of response in inborn errors of immunity.

Rubén Berrueco, Elisa González-Forster, Angela Deya-Martinez, María Solsona, Ana García-García, Joan Calzada-Hernández, Luo Yiyi, Alexandru Vlagea, Anna Ruiz-Llobet, Laia Alsina

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. An integrated sampling strategy for therapeutic mycophenolic acid monitoring in lung transplant recipients.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Rubén BerruecoPediatric Hematology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
Elisa González-ForsterPediatric Hematology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
Angela Deya-MartinezInstitut de Recerca Sant Joan de Déu de Barcelona (IRSJD), Barcelona, Spain.
María SolsonaPediatric Hematology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
Ana García-GarcíaInstitut de Recerca Sant Joan de Déu de Barcelona (IRSJD), Barcelona, Spain.
Joan Calzada-HernándezPediatric Rheumatology Unit, Hospital Sant Joan de Déu, Universitat de Barcelona, Barcelona, Spain.
Luo YiyiClinical Immunology and Primary Immunodeficiencies Unit, Pediatric Allergy and Clinical Immunology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
Alexandru VlageaClinical Immunology Unit, Hospital Sant Joan de Déu-Hospital Clínic Barcelona, Barcelona, Spain.
Anna Ruiz-LlobetPediatric Hematology Department, Hospital Sant Joan de Déu, Barcelona, Spain.
Laia AlsinaInstitut de Recerca Sant Joan de Déu de Barcelona (IRSJD), Barcelona, Spain.
Hospital Sant Joan de Déu Barcelona · ESDepartament de Salut · ESHospital Clínic de Barcelona · ESInstituto de Investigación de Enfermedades Raras · ESInstituto de Salud Carlos III · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Second-line treatments of autoimmune cytopenias (AC) are not well-defined in children. Mycophenolate mofetil (MMF) is an immunosuppressant agent that has been demonstrated to be safe and effective in this setting. A retrospective observational study was conducted in 18 children with prolonged AC who received MMF, in order to describe clinical and biological markers of response. The overall response rate of MMF at 20-30 mg/kg per day was 73.3%. All patients with Evans syndrome (

Indexed as

autoimmune diseasesautoimmune hemolytic anemiaautoimmune thrombocytopeniaEvans syndromemycophenolate mofetilpediatrics

Identifiers

PMID37915985
PMCPMC10616248
OpenAlexW4387694695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.