ArticleClinical kidney journal2023
Effects of oral nutritional supplements on the nutritional status and inflammatory markers in patients on maintenance dialysis: a systematic review and meta-analysis of randomized clinical trials.
Article in Clinical kidney journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Pooled it
- Effects of probiotic supplementation on bone health in postmenopausal women: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- The effect of different timings of protein supplementation on variable outcomes in hemodialysis patients: a randomized clinical trial.Clinical and experimental nephrology · 2025Trial
- The impact of predialytic oral protein-based supplements on nutritional status and quality of life in hemodialysis patients: a randomized clinical trial.BMC nephrology · 2025Trial
- Intradialytic oral nutrition effects on malnourished hemodialysis patients: a randomized trial.Scientific reports · 2024Trial
- An International Expert Consensus Statement and Guidance Document on Implementation of Nutritional Supplementation in Patients on Dialysis.Kidney international reports · 2026Article
- Ten tips for the first hemodialysis sessions.Clinical kidney journal · 2026Review
- Dialysis Adequacy, Nutritional Target Attainment, and Intradialytic Amino Acid Loss in Maintenance Hemodialysis Patients: Implications for Clinical Management.Healthcare (Basel, Switzerland) · 2026Article
- Comment on "Intradialytic protein supplementation: fish vs whey protein in hemodialysis patients".International urology and nephrology · 2026Article
- Effect of a home-based supervised personalised diet on malnutrition and frailty in dialysis patients: a randomised controlled trial.BMC nutrition · 2026Article
- Assessment of Hospitalized Patients' Awareness Regarding Food for Special Medical Purposes.Nutrients · 2026Article
- Sarcopenia, sarcopenic obesity, and frailty in individuals with chronic kidney disease: a comprehensive review.Kidney research and clinical practice · 2026Article
- Nutritional and Metabolic Interventions to Prevent and Treat Protein-Energy Wasting in Nondialysis CKD-Narrative Review.Nutrients · 2026Review
- Structured proactive nutritional care delivered via a digital follow-up platform is associated with better postoperative outcomes in gastric cancer patients after radical gastrectomy.Frontiers in oncology · 2026Article
- Machine learning-based prediction of hernia risk in peritoneal dialysis patients: a comparative study of models and SHAP-driven interpretability analysis.Frontiers in medicine · 2026Article
- Global Research on Hemodialysis Nutrition and Patient-Centered Priorities: A Bibliometric Analysis (2006-2025).Healthcare (Basel, Switzerland) · 2025Article
- Oral Nutritional Supplement Adherence and Nutritional Outcomes in Hemodialysis Patients-A Prospective Study.Journal of clinical medicine · 2025Article
- Morphofunctional Assessment of Malnutrition and Sarcopenia Using Nutritional Ultrasonography in Patients Undergoing Maintenance Hemodialysis.Medicina (Kaunas, Lithuania) · 2025Article
- Dialysis in the Elderly: A Practical Guide for the Clinician.International journal of nephrology · 2025Review
- Biomarker-Guided Dietary Supplementation: A Narrative Review of Precision in Personalized Nutrition.Nutrients · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Patients on hemodialysis (HD) or peritoneal dialysis (PD) often have insufficient energy and protein intake, resulting in poor nutritional status and adverse outcomes. Oral nutritional supplements (ONSs) are the most commonly used to increase such patients' energy and protein intakes. Methods: In this systematic review and meta-analysis, we analyzed studies on nutritional status, inflammatory markers, and electrolyte levels in patients on dialysis receiving ONSs. We searched four electronic databases from inception until 31 December 2022, for randomized controlled trials comparing ONS treatment versus placebo or routine care. Results: 22 studies with 1185 patients on dialysis were included in our meta-analysis. Compared with the control group, the ONS group exhibited significantly increased serum albumin levels [1.26 g/l (95%CI, 0.50-2.02, Conclusion: In conclusion, ONS use can improve the nutritional status of patients on dialysis in terms of their serum albumin, BMI, and HGS without significant effects on serum phosphorus, potassium, and C-reactive protein levels. However, it remains uncertain whether these results translate to improvement in clinically relevant outcomes. Large-scale high-quality studies are still required in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.