Evidence map›Paper›PMID 37915638›Full record

ArticleAnnals of medicine and surgery (2012)2023

Olfactory and gustatory dysfunction, evaluation and the impact on quality of life among COVID-19 patients: a multi-centre study.

Abdulaziz Saud AlEnazi, Maha Abdullah Alharbi, Danah Hamdan Althomaly, Mona Mohammed Saleh Ashoor, Marwan Jaber Alwazzeh, Roa Talal Halawani, Lamia Abdulwahab Buohliqah, Laila Mohammed Telmesani

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Abdulaziz Saud AlEnaziDepartments ofOtolaryngology-Head and Neck surgery.
Maha Abdullah AlharbiDepartment of Otolaryngology-Head and Neck Surgery, Ministry of Health, Al-Khobar.
Danah Hamdan AlthomalyDepartment of Otolaryngology-Head and Neck Surgery, Ministry of Health, Al-Khobar.
Mona Mohammed Saleh AshoorDepartments ofOtolaryngology-Head and Neck surgery.
Marwan Jaber AlwazzehInternal Medicine, College of Medicine, King Fahad Hospital of the University, Al-Khobar, Imam Abdulrahman Bin Faisal University, Dammam.
Roa Talal HalawaniDepartment of Otorhinolaryngology-Head and Neck Surgery ,Ohud General Hospital, Ministry of Health, AL Medina.
Lamia Abdulwahab BuohliqahDepartment of Otorhinolaryngology-Head and Neck Surgery, Qatif Center Hospital, Ministry of Health, AL Qatif, Saudi Arabia.
Laila Mohammed TelmesaniDepartments ofOtolaryngology-Head and Neck surgery.
Imam Abdulrahman Bin Faisal University · SAFederal Ministry of Health · SDKing Fahd Hospital of the University · SAMedina General Hospital · PHOphthalmology Associates (United States) · USQatif Central Hospital · SASaad Specialist Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Olfactory and gustatory dysfunctions are frequently reported symptoms among COVID-19 patients. However, several reports suggested that there might be significant variation in the prevalence and clinical picture of chemosensory dysfunction in COVID-19 patients among different population. Objective: To study the prevalence of chemosensory dysfunction, recovery time and its impact on quality of life (QoL) among COVID-19 patients in Saudi population. Methods: This multi-centre observational study was conducted at three COVID-19 centres in Saudi Arabia. Epidemiological and clinical data were extracted at baseline and within the 2-month post-infection. Olfactory and gustatory dysfunctions were assessed via valid taste and smell questionnaire, electronically collected via online survey. Short version of questionnaire of Olfactory disorders-negative statements (sQOD-NS) was used to assess the impact on QoL. Result: Total 1734 patients [926 males and 808 females, the mean age of patients was 37.7±11.6 years] with laboratory confirmed COVID-19 were recruited for this study. Chemosensory dysfunction was reported in 56.5% cases. olfactory and gustatory dysfunctions were significantly high in females (66.2%) and age group younger than or equal to 40 years (62.2%). Among patients with olfactory dysfunction and gustatory dysfunction, recovery rate was 757 (77.2%) and 702 (71.6%). Furthermore, the recovery time was within 8 days of onset of symptoms in 53.6% and 61.3% of olfactory dysfunction and gustatory dysfunction cases, respectively. Overall mean QoL score indicated Olfactory and gustatory dysfunction has significant impact on QoL [11.3±6.2 ( Conclusion: Chemosensory dysfunction among Saudi population was comparable to the European data and significantly higher than Asian supporting the fact that these symptoms vary as per ethnicity. Olfactory and gustatory dysfunction significantly impaired QoL and could present as an early symptom of COVID-19. Recovery rate of these symptoms can serve as a good prognostic data for patient's counselling. Further long-term follow-up studies would lead to better understanding of prognosis and clinical outcomes.

Indexed as

chemosensorycoronavirusCOVID-19gustatoryolfactory dysfunction

Identifiers

PMID37915638
PMCPMC10617925
OpenAlexW4386847657

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.