Evidence map›Paper›PMID 37915405›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2023

Fully automated pipeline for measurement of the thoracic aorta using joint segmentation and localization neural network.

Sudeep Katakol, Timothy J Baker, Zhangxing Bian, Yanglong Lu, Greg Spahlinger, Charles R Hatt, Nicholas S Burris

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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  3. Article
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  5. Distal anastomotic new entry tears predict long-term outcomes after hemi-arch repair for DeBakey I aortic dissection†.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sudeep KatakolUniversity of Michigan, Department of Electrical and Computer Engineering, Ann Arbor, Michigan, United States.ORCID https://orcid.org/0000-0002-4421-9819
Timothy J BakerUniversity of Michigan, Department of Radiology, Ann Arbor, Michigan, United States.ORCID https://orcid.org/0000-0001-9427-3840
Zhangxing BianJohns Hopkins University, Department of Electrical and Computer Engineering, Baltimore, Maryland, United States.
Yanglong LuUniversity of Michigan, Department of Radiology, Ann Arbor, Michigan, United States.ORCID https://orcid.org/0000-0001-6911-651X
Greg SpahlingerUniversity of Michigan, Department of Radiology, Ann Arbor, Michigan, United States.
Charles R HattImbio Inc., Minneapolis, Minnesota, United States.ORCID https://orcid.org/0000-0001-7097-5434
Nicholas S BurrisUniversity of Michigan, Department of Radiology, Ann Arbor, Michigan, United States.ORCID https://orcid.org/0000-0002-5198-4383

Funding

Vascular Deformation Mapping (VDM) for Automated, 3D Assessment of Thoracic Aortic AneurysmR44HL145953 · NHLBI · IMBIO, LLC · PI BURRIS, NICHOLAS SCOTT, HATT, CHARLES R · 2019 to 2022
$1.5M
NHLBI NIH HHS R44 HL145953
6 · The paper itself

Abstract

Purpose: Diagnosis and surveillance of thoracic aortic aneurysm (TAA) involves measuring the aortic diameter at various locations along the length of the aorta, often using computed tomography angiography (CTA). Currently, measurements are performed by human raters using specialized software for three-dimensional analysis, a time-consuming process, requiring 15 to 45 min of focused effort. Thus, we aimed to develop a convolutional neural network (CNN)-based algorithm for fully automated and accurate aortic measurements. Approach: Using 212 CTA scans, we trained a CNN to perform segmentation and localization of key landmarks jointly. Segmentation mask and landmarks are subsequently used to obtain the centerline and cross-sectional diameters of the aorta. Subsequently, a cubic spline is fit to the aortic boundary at the sinuses of Valsalva to avoid errors related inclusions of coronary artery origins. Performance was evaluated on a test set of 60 scans with automated measurements compared against expert manual raters. Result: Compared to training separate networks for each task, joint training yielded higher accuracy for segmentation, especially at the boundary ( Conclusion: Fully automated aortic diameter measurements in TAA are feasible using a CNN-based algorithm. Automated measurements demonstrated low errors that are comparable in magnitude to those with manual raters; however, measurement error was highest in the aortic root and arch.

Indexed as

aneurysmaortaaortic diameterlocalizationsegmentation

Identifiers

PMID37915405
PMCPMC10617550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.