Evidence map›Paper›PMID 37915377›Full record

ArticleSynthesis2023

Palladium-Catalyzed Dearomatization of Benzothiophenes: Isolation and Functionalization of a Discrete Dearomatized Intermediate.

Andrew John Intelli, Mohan Pal, Manikandan Selvaraju, Ryan A Altman

Abstract read
In one paragraph

Article in Synthesis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew John IntelliDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-3987-4464
Mohan PalNuChem Sciences Inc.; 2350 Rue Cohen Suite 201, Saint-Laurent, Quebec, Canada H4R 2N6.
Manikandan SelvarajuExemplify Biopharma; 1002 Eastpark Blvd, Cranbury, NJ, 08512, United States.ORCID 0000-0003-1262-6089
Ryan A AltmanDepartment of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States.ORCID 0000-0002-8724-1098

Funding

Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SUSAN J. BROWN · 2012 to 2026
$63.0M
Grant Supplement to Support Diversity in Health-Related ResearchR35GM124661 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI Ryan A Altman · 2017 to 2026
$4.1M
AVIII HD 400 NMR spectrometer to replace existing DRX 400S10OD016360 · OD · UNIVERSITY OF KANSAS LAWRENCE · PI DOUGLAS, JUSTIN TRIGALET · 2014 to 2014
$297k
NIGMS NIH HHS P20 GM103418NIGMS NIH HHS R35 GM124661NIH HHS S10 OD016360
6 · The paper itself

Abstract

A Pd-catalyzed decarboxylative dearomatization reaction of a heterocyclic substrate enables access to an uncommon reaction intermediate that rearomatizes in the presence of amine bases in a net C-H functionalization sequence. The dearomatized benzo[

Indexed as

C–H functionalizationDearomatizationDecarboxylationHeterocyclesTransition-metal

Identifiers

PMID37915377
PMCPMC10617892

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.