Evidence map›Paper›PMID 37915103›Full record

ReviewEuropean journal of medical research2023

The emerging roles of N6-methyladenosine RNA modifications in thyroid cancer.

Xiaoxin Xu, Jiayao Zhao, Mingyue Yang, Lutuo Han, Xingxing Yuan, Wencheng Chi, Jiakang Jiang

Open access · goldAbstract readReview
In one paragraph

Review in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoxin Xu *Heilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang, People's Republic of China.
Jiayao Zhao *Heilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang, People's Republic of China.
Mingyue YangThe Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Lutuo HanHeilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang, People's Republic of China.
Xingxing YuanHeilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang, People's Republic of China.
Wencheng ChiHeilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang, People's Republic of China. 15104535400@163.com.
Jiakang JiangHeilongjiang University of Chinese Medicine, Harbin, 150040, Heilongjiang, People's Republic of China. jiangjiakang1964@163.com.
Heilongjiang University of Chinese Medicine · CNHeilongjiang Academy of Forestry · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid cancer (TC) is the most predominant malignancy of the endocrine system, with steadily growing occurrence and morbidity worldwide. Although diagnostic and therapeutic methods have been rapidly developed in recent years, the underlying molecular mechanisms in the pathogenesis of TC remain enigmatic. The N6-methyladenosine(m6A) RNA modification is designed to impact RNA metabolism and further gene regulation. This process is intricately regulated by a variety of regulators, such as methylases and demethylases. Aberrant m6A regulators expression is related to the occurrence and development of TC and play an important role in drug resistance. This review comprehensively analyzes the effect of m6A methylation on TC progression and the potential clinical value of m6A regulators as prognostic markers and therapeutic targets in this disease.

Indexed as

Thyroid NeoplasmsHumansRNARNAN6-MethyladenosinePrognosisProgressionThyroid cancerTreatment

Identifiers

PMID37915103
PMCPMC10621220
OpenAlexW4388141589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.