Evidence map›Paper›PMID 37914969›Full record

Observational studyCanadian journal of anaesthesia = Journal canadien d'anesthesie2024

Capnography access and use in Kenya and Ethiopia.

Maziar M Nourian, Amany Alshibli, John Kamau, Susan Nabulindo, Dennis A Amollo, Jennifer Connell, Svetlana K Eden, Rahel Seyoum, Masresha G Teklehaimanot, Gebrehiwot A Tegu and 3 more

Abstract readObservational Study
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Observational study in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Maziar M NourianDepartment of Anesthesiology, Vanderbilt University Medical Center, 1211 Medical Center Drive, Nashville, TN, 37232, USA. maziarnourian@gmail.com.ORCID 0000-0002-3335-9357
Amany AlshibliDepartment of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, CA, USA.
John KamauAfrican Mission Healthcare, ImPACT Africa-Tanzania, Nairobi, Kenya.
Susan NabulindoDepartment of Anesthesiology, University of Nairobi, Nairobi, Kenya.
Dennis A AmolloAfrican Population and Health Research Center, Nairobi, Kenya.
Jennifer ConnellVanderbilt University School of Medicine, Nashville, TN, USA.
Svetlana K EdenDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Rahel SeyoumDepartment of Anesthesiology, Bahir Dar University, Bahir Dar, Ethiopia.
Masresha G TeklehaimanotDepartment of Anesthesiology, Mekelle University, Mekelle, Ethiopia.
Gebrehiwot A TeguDepartment of Anesthesiology, Bahir Dar University, Bahir Dar, Ethiopia.
Haftom B DestaDepartment of Anesthesiology, Mekelle University, Mekelle, Ethiopia.
Mark NewtonDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.
Bantayehu SileshiDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLack of access to safe and affordable anesthesia and monitoring equipment may contribute to higher rates of morbidity and mortality in low- and middle-income countries (LMICs). While capnography is standard in high-income countries, use in LMICs is not well studied. We evaluated the association of capnography use with patient and procedure-related characteristics, as well as the association of capnography use and mortality in a cohort of patients from Kenya and Ethiopia.

methodsFor this retrospective observational study, we used historical cohort data from Kenya and Ethiopia from 2014 to 2020. Logistic regression was used to study the association of capnography use (primary outcome) with patient/procedure factors, and the adjusted association of intraoperative, 24-hr, and seven-day mortality (secondary outcomes) with capnography use.

resultsA total of 61,792 anesthetic cases were included in this study. Tertiary or secondary hospital type (compared with primary) was strongly associated with use of capnography (odds ratio [OR], 6.27; 95% confidence interval [CI], 5.67 to 6.93 and OR, 6.88; 95% CI, 6.40 to 7.40, respectively), as was general (vs regional) anesthesia (OR, 4.83; 95% CI, 4.41 to 5.28). Capnography use was significantly associated with lower odds of intraoperative mortality in patients who underwent general anesthesia (OR, 0.31; 95% CI, 0.17 to 0.48). Nevertheless, fully-adjusted models for 24-hr and seven-day mortality showed no evidence of association with capnography.

conclusionCapnography use in LMICs is substantially lower compared with other standard anesthesia monitors. Capnography was used at higher rates in tertiary centres and with patients undergoing general anesthesia. While this study revealed decreased odds of intraoperative mortality with capnography use, further studies need to confirm these findings.

Indexed as

Anesthesia, ConductionCapnographyAnesthesia, GeneralEthiopiaHumansKenyacapnographyend-tidal carbon dioxidelow-resource-settingsperioperative mortality

Identifiers

PMID37914969

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.