Evidence map›Paper›PMID 37914962›Full record

ArticleApplied biochemistry and biotechnology2024

Fermentative Production of β-Carotene from Sugarcane Bagasse Hydrolysate by Rhodotorula glutinis CCT-2186.

Erick Díaz-Ruiz, Thércia R Balbino, Júlio C Dos Santos, Vinod Kumar, Silvio S da Silva, Anuj K Chandel

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Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Erick Díaz-RuizDepartment of Biotechnology, Engineering School of Lorena, University of São Paulo (EEL-USP), 12.602.810, Lorena, SP, Brazil.
Thércia R BalbinoDepartment of Biotechnology, Engineering School of Lorena, University of São Paulo (EEL-USP), 12.602.810, Lorena, SP, Brazil.
Júlio C Dos SantosDepartment of Biotechnology, Engineering School of Lorena, University of São Paulo (EEL-USP), 12.602.810, Lorena, SP, Brazil.
Vinod KumarSchool of Water, Energy and Environment, Cranfield University, Cranfield, MK43 0AL, UK.
Silvio S da SilvaDepartment of Biotechnology, Engineering School of Lorena, University of São Paulo (EEL-USP), 12.602.810, Lorena, SP, Brazil.
Anuj K ChandelDepartment of Biotechnology, Engineering School of Lorena, University of São Paulo (EEL-USP), 12.602.810, Lorena, SP, Brazil. anuj10@usp.br.ORCID http://orcid.org/0000-0002-2136-2620
Universidade de São Paulo · BRCranfield University · GB

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 309214/2021-1Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.514236/2020-00
6 · The paper itself

Abstract

Β-Carotene is a red-orange pigment that serves as a precursor to important pharmaceutical molecules like vitamin A and retinol, making it highly significant in the industrial sector. Consequently, there is an ongoing quest for more sustainable production methods. In this study, glucose and xylose, two primary sugars derived from sugarcane bagasse (SCB), were utilized as substrates for β-carotene production by Rhodotorula glutinis CCT-2186. To achieve this, SCB underwent pretreatment using NaOH, involved different concentrations of total solids (TS) (10%, 15%, and 20%) to remove lignin. Each sample was enzymatically hydrolyzed using two substrate loadings (5% and 10%). The pretreated SCB with 10%, 15%, and 20% TS exhibited glucose hydrolysis yields (%wt) of 93.10%, 91.88%, and 90.77%, respectively. The resulting hydrolysate was employed for β-carotene production under batch fermentation. After 72 h of fermentation, the SCB hydrolysate yielded a β-carotene concentration of 118.56 ± 3.01 mg/L. These findings showcase the robustness of R. glutinis as a biocatalyst for converting SCB into β-carotene.

Indexed as

beta CaroteneCelluloseFermentationRhodotorulaSaccharumGlucoseHydrolysisXylosebagassebeta CaroteneCelluloseGlucoseXyloseEnzymatic hydrolysisFermentationPretreatmentRhodotorula glutinisSugarcane bagasseβ-Carotene

Identifiers

PMID37914962
OpenAlexW4388229373

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.