Evidence map›Paper›PMID 37914946›Full record

ArticleNature2023

Carbon-to-nitrogen single-atom transmutation of azaarenes.

Jisoo Woo, Colin Stein, Alec H Christian, Mark D Levin

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
26.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 175 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Lactam Framework Editing via Formal Methylene Deletion.Journal of the American Chemical Society · 2026
    Article
  8. Review
  9. Shape-Conserving Atom Replacements.Chemical reviews · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jisoo WooDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID 0000-0001-7356-9458
Colin SteinDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID 0009-0005-1990-4426
Alec H ChristianDiscovery Chemistry, Merck & Co., Inc., Boston, MA, USA. alec.christian@merck.com.ORCID 0000-0002-7032-230X
Mark D LevinDepartment of Chemistry, The University of Chicago, Chicago, IL, USA. marklevin@uchicago.edu.ORCID 0000-0002-4461-363X
University of Chicago · USMerck & Co., Inc., Rahway, NJ, USA (United States) · US

Funding

Construction of Heteroarenes Through Single Atom I-RenewalR35GM142768 · NIGMS · UNIVERSITY OF CHICAGO · PI Mark Daniel Levin · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM142768
6 · The paper itself

Abstract

When searching for the ideal molecule to fill a particular functional role (for example, a medicine), the difference between success and failure can often come down to a single atom

Indexed as

CarbonChemistry Techniques, SyntheticNitrogenQuinazolinesQuinolinesDrug DesignOxidation-ReductionPharmaceutical PreparationsCarbonNitrogenPharmaceutical PreparationsQuinazolinesQuinolines

Identifiers

PMID37914946
PMCPMC10907950
OpenAlexW4388126449

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.