Evidence map›Paper›PMID 37914939›Full record

ArticleNature2023

IL-1β

Nicoletta Caronni, Federica La Terza, Francesco M Vittoria, Giulia Barbiera, Luca Mezzanzanica, Vincenzo Cuzzola, Simona Barresi, Marta Pellegatta, Paolo Canevazzi, Garett Dunsmore and 30 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 256 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
256citing papers in PubMed, 1 pooled it
51.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

256 citing papers in PubMed, 1 synthesis or guideline pooled it, 316 citations in OpenAlex.

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196 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 8 institutions in 4 countries.

Nicoletta Caronni *San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy. caronni.nicoletta@hsr.it.ORCID 0000-0002-3263-7108
Federica La Terza *San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-6129-6015
Francesco M Vittoria *San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Giulia Barbiera *San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Luca MezzanzanicaSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Vincenzo CuzzolaSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Simona BarresiSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marta PellegattaIRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-1977-1369
Paolo CanevazziIRCCS San Raffaele Scientific Institute, Milan, Italy.
Garett DunsmoreINSERM U1015, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.
Carlo LeonardiSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Elisa MontaldoSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0001-9293-0683
Eleonora LusitoSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Erica DugnaniDiabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Antonio CitroDiabetes Research Institute (DRI), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-0947-7687
Melissa S F NgSingapore Immunology Network (SIgN), A*STAR, Singapore, Singapore.ORCID 0000-0003-3826-2746
Marco Schiavo LenaIRCCS San Raffaele Scientific Institute, Milan, Italy.
Denise DragoCenter for Omics Sciences (COSR), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Annapaola AndolfoCenter for Omics Sciences (COSR), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-0566-2391
Silvia BrugiapagliaDepartment of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-8159-0449
Alessandro ScagliottiDepartment of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.ORCID 0000-0002-7604-6270
Alessandra MortellaroSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-1744-2430
Vincenzo CorboUniversity of Verona, Verona, Italy.ORCID 0000-0002-6340-8009
Zhaoyuan LiuShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Anna MondinoIRCCS San Raffaele Scientific Institute, Milan, Italy.
Paolo DellabonaIRCCS San Raffaele Scientific Institute, Milan, Italy.
Lorenzo PiemontiVita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0002-2172-2198
Carla TaveggiaIRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-6531-9544
Claudio DoglioniVita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0002-4969-5216
Paola CappelloDepartment of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.
Francesco NovelliDepartment of Molecular Biotechnology and Health Sciences, University of Turin, Turin, Italy.
Matteo IannaconeVita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0002-9370-2671
Lai Guan NgShanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-1905-3586
Florent GinhouxINSERM U1015, Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.
Stefano CrippaVita-Salute San Raffaele University, Milan, Italy.
Massimo FalconiVita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0001-9654-7243
Chiara BoniniVita-Salute San Raffaele University, Milan, Italy.ORCID 0000-0002-0772-1674
Luigi NaldiniSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-7835-527X
Marco GenuaSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-0764-8163
Renato OstuniSan Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, Milan, Italy. ostuni.renato@hsr.it.ORCID 0000-0003-0460-3426
Vita-Salute San Raffaele University · ITThe San Raffaele Telethon Institute for Gene Therapy · ITUniversity of Turin · ITAgency for Science, Technology and Research · SGIstituti di Ricovero e Cura a Carattere Scientifico · ITShanghai Jiao Tong University · CNInserm · FRUniversity of Verona · IT

Funding

European Research Council
6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with high resistance to therapies

Indexed as

InflammationInterleukin-1betaPancreatic NeoplasmsTumor-Associated MacrophagesCarcinogenesisCarcinoma, Pancreatic DuctalDinoprostoneDisease ProgressionGene Expression Regulation, NeoplasticHumansTumor MicroenvironmentTumor Necrosis FactorsDinoprostoneInterleukin-1betaTumor Necrosis Factors

Identifiers

PMID37914939
OpenAlexW4388126446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.