ArticleNature2023
Structure of the native myosin filament in the relaxed cardiac sarcomere.
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Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.
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0cells of the map it votes in
101citing papers in PubMed
31.6field-weighted citation impact, top 1% of its field
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Who cites it
101 citing papers in PubMed, 144 citations in OpenAlex.
- Piperine disrupts the OFF state of the resting thick filament of rat skeletal muscle, enhancing dynamic contractility in a fibre-type-dependent manner.The Journal of physiology · 2026Article
- The structure of the native cardiac crossbridge in the rigor state.Science advances · 2026Article
- Probing relaxed myosin states in hypertrophic cardiomyopathy by second harmonic-generation microscopy.eLife · 2026Article
- Myosin motor dynamics and cardiac function: Insights from in vivo small-angle X-ray scattering and pressure-volume analysis.The Journal of physiology · 2026Article
- Polarized Light Microscopy for Quantitative Assessment of Sarcomere-Scale Structural Order in Cardiac Tissue.Journal of biophotonics · 2026Article
- A manufacturability-informed topology framework for AI-guided design of fibrous network materials.Nature communications · 2026Article
- Article
- Higher-order structural organization of mitochondrial metabolism.The Journal of biological chemistry · 2026Review
- Mavacamten shows broad benefit in human and mouse models of MYBPC3-related hypertrophic cardiomyopathy.Nature cardiovascular research · 2026Article
- Mechanotransduction Failure and Molecular Rescue in Gastric Cancer: Kinetotherapy Across the IL-6/STAT3-Myostatin/ACVR2B-Akt/mTOR Axis.Medical sciences (Basel, Switzerland) · 2026Review
- Subsarcomeric regulation of thin and thick filaments in skeletal muscle myofibrils.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Dynamics of the β-cardiac myosin auto-inhibited state explain cardiomyopathy pathogenesis.Nature communications · 2026Article
- Why labelling the 'fast-reacting thiols' of myosin reduces force output: re-assessing a year at the University of California San Francisco (1987-8).Biophysical reviews · 2026Review
- Selective titin cleavage disrupts cardiac mechanical homeostasis to drive heart failure and fibrosis.Nature cardiovascular research · 2026Article
- Solution NMR study of the titin I-band IgI domain I82 shows unusual conformational dynamics.Journal of biomolecular NMR · 2026Article
- The thin line between biochemistry and structure where myosin super relaxed state lies.Biophysical reviews · 2026Review
- "QuickStainer": a rapid negative staining device for improved preservation of molecular structure.Journal of structural biology · 2026Article
- Porcine Left Atrial and Ventricular Thick Filaments Exhibit Distinct Resting Structures and Calcium-dependent Responses.bioRxiv : the preprint server for biology · 2026Article
- Titin's P-zone domains A164-167 are essential for thick filament structural arrangement.The Journal of general physiology · 2026Article
- Distinct distributions of myosin motor conformations during contraction of slow and fast skeletal muscle.The Journal of physiology · 2026Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Davide TamborriniDepartment of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
Zhexin WangDepartment of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.ORCID 0000-0002-4256-1143
Thorsten WagnerDepartment of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.ORCID 0000-0002-1550-8275
Sebastian TackeDepartment of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
Markus StabrinDepartment of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.
Michael GrangeDepartment of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany.ORCID 0000-0003-2580-2299
Ay Lin KhoRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, Kings College London BHF Centre of Research Excellence, London, UK.ORCID 0000-0002-9753-2091
Martin ReesRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, Kings College London BHF Centre of Research Excellence, London, UK.
Pauline BennettRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, Kings College London BHF Centre of Research Excellence, London, UK.
Mathias GautelRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, Kings College London BHF Centre of Research Excellence, London, UK.ORCID 0000-0003-4027-9803
Stefan RaunserDepartment of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, Germany. stefan.raunser@mpi-dortmund.mpg.de.ORCID 0000-0001-9373-3016
Max Planck Institute of Molecular Physiology · DEKing's College London · GBMRC Laboratory of Molecular Biology · GBRosalind Franklin Institute · GB
Funding
British Heart Foundation CH/08/001/25300British Heart Foundation RG/15/8/31480British Heart Foundation RG/F/22/110079Medical Research Council MR/R003106/1Wellcome Trust
Abstract
The thick filament is a key component of sarcomeres, the basic units of striated muscle
Indexed as
Cardiac MyosinsMyocardiumSarcomeresConnectinCryoelectron MicroscopyElectron Microscope TomographyMyosin Binding Protein CCardiac MyosinsConnectinMyosin Binding Protein C
Identifiers
What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.