ArticleNature2023
Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
20.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- Forensic pathological analysis of sudden cardiac death in 10 cases with congenital coronary ostial stenosis: a technical report.Forensic science, medicine, and pathology · 2026Pooled it
- Cerebral Blood Flow Dynamics in Neurogenic Orthostatic Hypotension: A Systematic Review and Meta-Analysis.Hypertension (Dallas, Tex. : 1979) · 2025Pooled it
- A prefrontal cortex-hypothalamus circuit for heart rate control in non-human primates.bioRxiv : the preprint server for biology · 2026Article
- Article
- Neurocardiology: Brain-Heart Interactions in the Heart.MedComm · 2026Review
- The critical role of gut-brain signalling in eating behaviour and obesity.Nature reviews. Gastroenterology & hepatology · 2026Review
- Comparative Cost-Utility and Clinical Efficacy of 5-HT3 Receptor Antagonists in Sufentanil-Based PCIA: A Propensity Score-Matched Analysis.Pain and therapy · 2026Article
- Heart-Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes.Comprehensive Physiology · 2026Article
- Hierarchical Studies in TRAP2 Mice Demonstrate that Neuronal Activation and Mitochondrial Networks Integration Constitute the Key Mechanism Underlying Painful Syncope.Neuroscience bulletin · 2026Article
- A Non-spinal Neural Circuit for Transmitting Information of Bladder Conditions.Neuroscience bulletin · 2026Article
- Neural Control of Tissue Perfusion: Emerging Evidence and Beyond.Current hypertension reports · 2026Review
- Primary cerebral autoregulation dysfunction: a distinct subtype of vasovagal syncope.Acta neurologica Belgica · 2026Article
- Temporal dynamic brain-heart interaction alterations associated with suicidal ideation in major depressive disorder.BMC psychiatry · 2026Article
- Optogenetic activation of liver-innervating vagal sensory neurons increases anxiety-like behavior in mice.Translational psychiatry · 2026Article
- Postoperative New-Onset Heart Block in Noncardiac Surgery: Model Development, Validation, and Long-Term Prognostic Analysis.JACC. Asia · 2026Article
- Hemodynamic and Electrophysiological Progression of the Rose Bengal Photothrombotic Stroke Model in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events.Science advances · 2026Article
- Case Report: Glossopharyngeal neuralgia secondary to syncope: insights into microvascular decompression treatment.Frontiers in surgery · 2026Article
- The vagus nerve as a neurovisceral interface: a comprehensive review.Frontiers in neuroscience · 2026Review
Corrections and comments
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Authors and funding
18 authors at 4 institutions in 1 country.
Jonathan W Lovelace *Department of Neurobiology, University of California, San Diego, CA, USA.ORCID 0000-0001-5734-6801
Jingrui Ma *Department of Neurobiology, University of California, San Diego, CA, USA.
Saurabh YadavDepartment of Neurobiology, University of California, San Diego, CA, USA.ORCID 0000-0003-2433-1149
Karishma ChhabriaDepartment of Physics, University of California, San Diego, CA, USA.
Hanbing ShenDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.ORCID 0000-0003-1259-9084
Zhengyuan PangDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.ORCID 0000-0003-0321-4891
Tianbo QiDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.
Ruchi SehgalDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.
Yunxiao ZhangDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.ORCID 0000-0003-2145-4151
Tushar BaliDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.
Thomas VaissiereUniversity of Florida-Scripps Biomedical Research, Jupiter, FL, USA.ORCID 0000-0001-9510-7510
Shawn TanDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.
Yuejia LiuDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.ORCID 0000-0001-9322-5871
Gavin RumbaughUniversity of Florida-Scripps Biomedical Research, Jupiter, FL, USA.
Li YeDepartment of Neuroscience, Scripps Research, La Jolla, CA, USA.ORCID 0000-0002-3077-802X
David KleinfeldDepartment of Neurobiology, University of California, San Diego, CA, USA.ORCID 0000-0001-9797-4722
Carsen StringerHHMI Janelia Research Campus, Ashburn, VA, USA.ORCID 0000-0002-9229-4100
Vineet AugustineDepartment of Neurobiology, University of California, San Diego, CA, USA. vaugustine@ucsd.edu.ORCID 0000-0003-4431-1663
Scripps Institution of Oceanography · USScripps Research Institute · USUniversity of California San Diego · USJanelia Research Campus · US
Funding
Scripps Translational Science InstituteUL1TR002550 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2018 to 2022
$28.9MProject 4U19NS123717 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LINNINGER, ANDREAS A · 2021 to 2025
$13.4MResilient versus fragile aspects of blood flow in the mammalian brainR35NS097265 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KLEINFELD, DAVID · 2017 to 2024
$6.8MModulating somatosensory network to target metabolic diseasesDP2DK128800 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI YE, LI · 2020 to 2020
$2.7MAmerican Heart Association-American Stroke Association 23SCEFIA1142397NCATS NIH HHS UL1 TR002550NIDDK NIH HHS DP2 DK128800NINDS NIH HHS R35 NS097265NINDS NIH HHS U19 NS123717
Abstract
Visceral sensory pathways mediate homeostatic reflexes, the dysfunction of which leads to many neurological disorders
Indexed as
HeartReflexSensory Receptor CellsSyncopeVagus NerveArea PostremaBradycardiaCardiac Output, LowEchocardiographyHeart RateHumansHypotensionLaser-Doppler FlowmetryNerve NetReceptors, Neuropeptide YSingle-Cell Gene Expression Analysisneuropeptide Y2 receptorReceptors, Neuropeptide Y
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.