ArticleNature2023
Glioma synapses recruit mechanisms of adaptive plasticity.
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In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 218 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
218citing papers in PubMed, 2 pooled it
33.6field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
218 citing papers in PubMed, 2 syntheses or guidelines pooled it, 227 citations in OpenAlex.
- Beyond motor: clinical manifestations of right hemisphere gliomas - a systematic review.Journal of neuro-oncology · 2026Pooled it
- Brain-Derived Neurotrophic Factor (BDNF) as a Potential Biomarker in Brain Glioma: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- Neuroligin-3-CSPG4 interaction maintains oligodendrocyte precursor cell progenitor state and promotes glioma proliferation through mechanotransduction.Nature neuroscience · 2026Article
- The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma.Immunology and cell biology · 2026Review
- The DIPG/DMG National Tumor Board: The power of advocacy.Neuro-oncology pediatrics · 2026Article
- Glioma microenvironment: Cellular crosstalk, immunosuppression, and novel therapeutic perspectives.Chinese medical journal · 2026Review
- Levetiracetam therapeutically targets GABAergic synapses in diffuse midline glioma.Nature medicine · 2026Article
- Oncohistone inhibition reshapes tumor-microenvironment communication in Diffuse Midline Glioma (DMG).bioRxiv : the preprint server for biology · 2026Article
- Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth.Cell · 2026Article
- Review
- Glioblastoma recurrence: An NGS-centered seed-soil framework.Neoplasia (New York, N.Y.) · 2026Article
- Targeting the miR-19b/PPP2R5E axis enhances temozolomide response in glioblastoma via ROS-induced DNA damage.British journal of cancer · 2026Article
- Harmonized Acquisition of Connectome MRI and Clinical Data for Stroke, Parkinson's Disease and Glioma: Delphi-Derived Protocol Recommendations by the European Academy of Neurology.European journal of neurology · 2026Review
- Cancer Neuroscience: From Local Neuro-Immune Microenvironments to Systemic Brain-Body Circuitry.MedComm · 2026Review
- Considering biological limitations of lesion network mapping.Nature neuroscience · 2026Article
- Targeting the nervous system: Mechanistic insights into neuro-tumor communication and therapeutic opportunities.Acta pharmaceutica Sinica. B · 2026Review
- Cell autonomous regional differences in oligodendrocyte lineage development and responses to oncohistone H3.3 K27M.Nature communications · 2026Article
- Targeting tumour-neuron synapses with intracavitary RNA delivery prevents glioblastoma recurrence.Nature biomedical engineering · 2026Article
- Neural regulation in lung cancer: from mechanisms to new therapeutic perspectives.Clinical and experimental medicine · 2026Review
- Actin, connexin-43 and GAP-43 expression in gliomas: real-world associations with IDH status, tumor burden and survival.Journal of neuro-oncology · 2026Article
158 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
29 authors at 4 institutions in 2 countries.
Kathryn R TaylorDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5110-8703
Tara BarronDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Alexa HuiDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Avishay SpitzerDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0001-6551-9338
Belgin YalçinDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0001-9689-9062
Alexis E IvecDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Anna C GeraghtyDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Griffin G HartmannDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0001-9213-8995
Marlene ArztDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Shawn M GillespieDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Yoon Seok KimDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Samin Maleki JahanDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Helena ZhangDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0003-1873-9762
Kiarash ShamardaniDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-2548-705X
Minhui SuDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0001-5803-6098
Lijun NiDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Peter P DuDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Pamelyn J WooDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Arianna Silva-TorresDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Humsa S VenkateshDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0003-1194-3015
Rebecca MancusiDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0002-4809-5569
Anitha PonnuswamiDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Sara MulinyaweDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Michael B KeoughDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Isabelle ChauDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.ORCID 0000-0003-3733-4760
Razina Aziz-BoseDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA.
Itay TiroshDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0001-5477-2987
Mario L SuvàDepartment of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-9898-5351
Michelle MonjeDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, CA, USA. mmonje@stanford.edu.ORCID 0000-0002-3547-237X
Stanford University · USWeizmann Institute of Science · ILBroad Institute · USHoward Hughes Medical Institute · US
Funding
Targeting the Vasular SystemP50CA165962 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Benjamin Harris Kann · 2013 to 2026
$33.5MTargeting the neuronal microenvironment in glioblastomaU19CA264504 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI Tracy T Batchelor · 2021 to 2026
$6.4MGlioma Circuitry: Bridging Systems Neuroscience and CancerDP1NS111132 · NINDS · STANFORD UNIVERSITY · PI MONJE-DEISSEROTH, MICHELLE · 2018 to 2022
$5.7MNeuronal Regulation of Low-Grade GliomagenesisR01CA258384 · NCI · STANFORD UNIVERSITY · PI David H Gutmann, Michelle Monje-Deisseroth · 2022 to 2026
$3.1MNeuronal activity-regulated mechanisms of glioma growthR01NS092597 · NINDS · STANFORD UNIVERSITY · PI MONJE-DEISSEROTH, MICHELLE · 2016 to 2021
$2.1MNCI NIH HHS P50 CA165962NCI NIH HHS R01 CA258384NCI NIH HHS U19 CA264504NINDS NIH HHS DP1 NS111132NINDS NIH HHS R01 NS092597
Abstract
The role of the nervous system in the regulation of cancer is increasingly appreciated. In gliomas, neuronal activity drives tumour progression through paracrine signalling factors such as neuroligin-3 and brain-derived neurotrophic factor
Indexed as
Adaptation, PhysiologicalGliomaNeuronal PlasticitySynapsesAnimalsBrain-Derived Neurotrophic FactorCalcium-Calmodulin-Dependent Protein Kinase Type 2Cell ProliferationChildDisease ProgressionGlutamic AcidHumansMembrane GlycoproteinsNeuronsOptogeneticsReceptors, AMPABDNF protein, humanBrain-Derived Neurotrophic FactorCalcium-Calmodulin-Dependent Protein Kinase Type 2Glutamic AcidMembrane GlycoproteinsReceptors, AMPAReceptor, trkBtropomyosin-related kinase-B, human
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.