Evidence map›Paper›PMID 37914632›Full record

ArticleSleep health2024

Mood correlates with circadian alignment in healthy individuals.

Jonathan S Emens, Alfred J Lewy

Abstract read
In one paragraph

Article in Sleep health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jonathan S EmensDepartment of Psychiatry, Oregon Health & Science University, Portland, Oregon, USA; Oregon Institute of Occupational Health Sciences, Portland, Oregon, USA; Division of Mental Health, VA Portland Health Care System, Portland, Oregon, USA. Electronic address: emensj@ohsu.edu.
Alfred J LewyDepartment of Psychiatry, Oregon Health & Science University, Portland, Oregon, USA.

Funding

YOUTH, Osteoporosis, and Understanding Total Health (YOUTH)M01RR000334 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI DORSA, DANIEL MICHAEL · 1985 to 2006
$30.6M
Melatonin Studies of Totaly Blind ChildrenR01HD042125 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWY, ALFRED J · 2002 to 2010
$2.5M
Melatonin for Circadian Sleep Disorders in the BlindR01EY018312 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWY, ALFRED J · 2007 to 2011
$1.9M
Melatonin Entrainment of Elderly Blind Free-runnersR01AG021826 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWY, ALFRED J · 2002 to 2006
$1.9M
MENTORED PATIENT-ORIENTED RESEARCH CAREER DEVELOPMENT AWARDK23RR017636 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI EMENS, JONATHAN S · 2003 to 2007
$649k
Inflammatory cytokine-mediated induction of HIV cardiomyopathyK01RR024120 · NCRR · HARVARD MEDICAL SCHOOL · PI YEARLEY, JENNIFER · 2007 to 2008
$246k
NCRR NIH HHS K01 RR024120NCRR NIH HHS K23 RR017636NCRR NIH HHS M01 RR000334NEI NIH HHS R01 EY018312NIA NIH HHS R01 AG021826NICHD NIH HHS R01 HD042125
6 · The paper itself

Abstract

objectiveTo determine whether there is a correlation between mood and the alignment between the timing of the circadian pacemaker (circadian phase) and the timing of sleep in healthy, euthymic individuals.

methodsParticipants were 25 first-year medical students (25.9 ± 3.3years, 16 females). Mood (Profile of Mood States, brief form) and circadian phase (salivary dim light melatonin onset) were assessed 4 times over 7weeks. Circadian alignment was determined using the dim light melatonin onset to average midsleep interval (phase angle difference).

resultsProfile of Mood States, brief form score and phase angle difference were correlated: later dim light melatonin onset relative to midsleep (shorter phase angle differences) was associated with worse mood (F

conclusionsThere is a correlation between circadian alignment and mood among healthy individuals as has been found in individuals with seasonal and nonseasonal depression. This finding has implications for the development, prevention and treatment of mood disorders.

Indexed as

Circadian RhythmMelatoninAffectFemaleHumansMaleMood DisordersSleepMelatoninCircadianCircadian misalignmentMoodSleep

Identifiers

PMID37914632
PMCPMC11031326

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.