Evidence map›Paper›PMID 37914379›Full record

ArticleUrology practice2024

Association of Frailty and Complications Following Prostate Biopsy: Results From a Population-Based, Privately Insured Cohort.

Kayvon Kiani, Simon P Kim, Rodrigo Rodrigues Pessoa, Boris Gershman, Christopher Gonzalez, Elizabeth Molina, Adam Warren, Rodrigo Donalisio DaSilva, Brian Chapin, Eric Ballon-Landa

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Urology practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Kayvon KianiDepartment of Surgery, Division of Urology, University of Colorado, Aurora, Colorado.
Simon P KimDepartment of Surgery, Division of Urology, University of Colorado, Aurora, Colorado.
Rodrigo Rodrigues PessoaDepartment of Urology, Mayo Clinic, Rochester, Minnesota.
Boris GershmanDivision of Urologic Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Christopher GonzalezDepartment of Urology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois.
Elizabeth MolinaPopulation Health Shared Resource (PHSR), University of Colorado Cancer Center, Aurora, Colorado.
Adam WarrenPopulation Health Shared Resource (PHSR), University of Colorado Cancer Center, Aurora, Colorado.
Rodrigo Donalisio DaSilvaDepartment of Surgery, Division of Urology, University of Colorado, Aurora, Colorado.
Brian ChapinDepartment of Urology, MD Anderson Cancer Center, Houston, Texas.
Eric Ballon-LandaDepartment of Surgery, Division of Urology, University of Colorado, Aurora, Colorado.
University of Colorado System · USUniversity of Colorado Cancer Center · USBeth Israel Deaconess Medical Center · USLoyola University Chicago · USMayo Clinic · USThe University of Texas MD Anderson Cancer Center · USUniversity of Colorado Anschutz Medical Campus · US

Funding

University of Colorado Cancer Center Support Grant - Lung Cancer Patient-Derived Xenografts with Autologous Human Immune SystemsP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · 1988 to 2026
$117.0M
NCI NIH HHS P30 CA046934
6 · The paper itself

Abstract

introductionProstate needle biopsy (PNBx) is essential for prostate cancer diagnosis, yet it is not without risks. We sought to assess patients who underwent PNBx using a claims-based frailty index to study the association between frailty and postbiopsy complications from a large population-based cohort. We hypothesized that increased frailty would be associated with adverse outcomes.

methodsUsing Market Scan, we identified all men who underwent PNBx from 2010 to 2015. Individuals were stratified by claims-based frailty index into 2 prespecified categories: not frail, frail. Complications occurring within 30 days from prostate biopsy requiring emergency department, clinic, or hospital evaluations constituted the primary outcome. Unadjusted and adjusted analyses identified patient covariates associated with complications.

resultsWe identified 193,490 patients who underwent PNBx. The mean age was 57.6 years (SD: 5.0). In all, 5% were prefrail, mildly frail, or moderately to severely frail. The rate of overall complications increased from 11.1% for not frail to 15.5% for frail men. After adjusting for covariates, individuals with any degree of frailty experienced a higher risk of overall complication (odds ratio [OR]: 1.29;

conclusionsFrailty was associated with a higher risk of complications for patients undergoing PNBx. Frailty assessment should be integrated into shared decision-making to limit the provision of potentially harmful care associated with prostate cancer screening.

Indexed as

FrailtyProstatic NeoplasmsBiopsyEarly Detection of CancerHumansInsurance, HealthMaleMiddle AgedProstateProstate-Specific AntigenProstate-Specific Antigenfrailtygeriatric urologyprostate cancer screeningrisk assessment

Identifiers

PMID37914379
PMCPMC11634022
OpenAlexW4388163009

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.