Evidence map›Paper›PMID 37914234›Full record

ArticleBMJ open respiratory research2023

Asthma-related emergency admissions and associated healthcare resource use in Alberta, Canada.

Irvin Mayers, Arsh Randhawa, Christina Qian, Manisha Talukdar, Mena Soliman, Pramoda Jayasingh, Karissa Johnston, Mohit Bhutani

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06705764 (Tezepelumab in the Treatment of Emergency Room Asthma in Adults), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06705764 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Tezepelumab in the Treatment of Emergency Room Asthma in Adults (TERAA): A Phase 4 Double-Blinded, Parallel-Group, Randomized Control Trial With an Open Label Extension

TypeinterventionalSponsorUniversity of AlbertaRan2026 to 2026Enrolled100ConditionsSevere AsthmaArmsTezepelumab, Placebo
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Irvin MayersDivision of Pulmonary Medicine, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada imayers@ualberta.ca.ORCID 0000-0003-3875-1961
Arsh RandhawaAstraZeneca Canada Inc, Mississauga, Ontario, Canada.
Christina QianBroadstreet HEOR, Vancouver, British Columbia, Canada.
Manisha TalukdarAstraZeneca Canada Inc, Mississauga, Ontario, Canada.
Mena SolimanAstraZeneca Canada Inc, Mississauga, Ontario, Canada.
Pramoda JayasinghBroadstreet HEOR, Vancouver, British Columbia, Canada.
Karissa JohnstonBroadstreet HEOR, Vancouver, British Columbia, Canada.
Mohit BhutaniDivision of Pulmonary Medicine, Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
AstraZeneca (Canada) · CAUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of real-world research assessing asthma management following asthma-related emergency department (ED) discharges. The objective of this study was to characterise follow-up care, healthcare resource use (HCRU) and medical costs following ED admissions in Alberta, Canada.

methodsA retrospective cohort study was conducted on adults with asthma using longitudinal population-based administrative data from Alberta Health Services. Adult patients with asthma and ≥1 ED admission from 1 April 2015 to 31 March 2020 were included. ED admissions, outpatient visits, hospitalisations and asthma-specific medication use were measured in the 30 days before and up to 90 days after each asthma-related ED admission. Mean medical costs attributable to each type of HCRU were summarised. All outcomes were stratified by patient baseline disease severity.

resultsAmong 128 063 patients incurring a total of 20 142 asthma-related ED visits, a substantial rate of ED readmission was observed, with 10% resulting in readmissions within 7 days and 35% within 90 days. Rates increased with baseline asthma severity. Despite recommendations for patients to be followed up with an outpatient visit within 2-7 days of ED discharge, only 6% were followed up within 7 days. The mean total medical cost per patient was $C8143 in the 30 days prior to and $C5407 in the 30 days after an ED admission.

conclusionsDespite recommendations regarding follow-up care for patients after asthma-related ED admissions, there are still low rates of outpatient follow-up visits and high ED readmission rates. New or improved multidimensional approaches must be integrated into follow-up care to optimise asthma control and prevent readmissions.

Indexed as

AsthmaHospitalizationAdultAlbertaDelivery of Health CareHumansRetrospective Studiesadministrative dataasthmaexacerbationsreadmissions

Identifiers

PMID37914234
PMCPMC10668303
OpenAlexW4388142690

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.