SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2023
Association of preserved ratio impaired spirometry with mortality: a systematic review and meta-analysis.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Association of preserved ratio impaired spirometry with mortality and cardiovascular diseases: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Oxidative stress-induced endothelial dysfunction drives mechanical and infectious lung injury: Therapeutic potential of kaempferol in males.Redox biology · 2026Article
- Prevalence of PRISm and COPD and associated factors in a university medical centre spirometry unit: a cross-sectional analysis.BMJ open · 2026Article
- Preserved Ratio Impaired Spirometry in Low- and Middle-Income Countries: An Emerging Cardiopulmonary Phenotype and Cardiovascular Risk-A Narrative Review.Life (Basel, Switzerland) · 2026Review
- Impact of preserved ratio impaired spirometry on postoperative outcomes of non-small cell lung cancer surgery.Scientific reports · 2026Article
- Asthma outcomes in adults with preserved ratio impaired spirometry: a cohort study.ERJ open research · 2026Article
- The role of diet and periodontitis in preserved ratio impaired spirometry: a mediation analysis.Frontiers in nutrition · 2026Article
- Traditional Chinese Exercise Improves Lung Function and Exercise Capacity in Patients with Preserved Ratio Impaired Spirometry.Chinese journal of integrative medicine · 2025Article
- Machine learning models using dual-phase CT radiomics for early detection of PRISm.Scientific reports · 2025Article
- Comprehensive Review of Comorbidities in Chronic Obstructive Pulmonary Disease and Preserved Ratio Impaired Spirometry: Insights from 2024.Tuberculosis and respiratory diseases · 2025Article
- Association between visceral lipid accumulation indicator and preserved ratio impaired spirometry in US adults: a population-based study from 2007 to 2012.Lipids in health and disease · 2025Article
- PRISm and the risk for all-cause mortality in relation to sleep disordered breathing: a community-based study.ERJ open research · 2025Article
- Risk of exacerbations, hospitalisation, and mortality in adults with physician-diagnosed chronic obstructive pulmonary disease with normal spirometry and adults with preserved ratio impaired spirometry in Sweden: retrospective analysis of data from a nationwide cohort study.The Lancet regional health. Europe · 2025Article
- Article
- Regional lung function assessment using electrical impedance tomography in COPD, PRISm, and normal spirometry subjects: insights into early diagnostic potential.BMC pulmonary medicine · 2025Article
- Proteins associated with preserved ratio impaired spirometry.ERJ open research · 2025Article
- Associations between life's essential 8 and preserved ratio impaired spirometry.Scientific reports · 2025Article
- Preserved ratio impaired spirometry: clinical, imaging and artificial intelligence perspective.Journal of thoracic disease · 2025Review
- Causal association between cigarette smoking and the prevalence of preserved ratio impaired spirometry (PRISm), and the progression risk factors of PRISm: A study based on Mendelian randomization and meta-analysis.Tobacco induced diseases · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreserved ratio impaired spirometry (PRISm) is prevalent within the general population. Increased mortality has been reported among subjects with PRISm, but the evidence has never been summarised. This systematic review aims to synthesise evidence on the association between PRISm and the risk of all-cause, cardiovascular and respiratory-related mortality.
methodsWe systematically searched MEDLINE, Embase and Web of Science for population-based cohort studies from inception to April 2023 using the terms related to impaired spirometry and mortality. Titles and abstracts were screened to identify eligible studies that reported mortality estimates for individuals with PRISm. We excluded studies that adopted other definitions of impaired spirometry, had a specific study setting (
resultsEight studies met the inclusion criteria involving 40 699 individuals with PRISm. All included studies reported increased risk of all-cause mortality among adults with PRISm. Meta-analysis showed that PRISm was associated with an increased risk of all-cause mortality (pooled HR 1.71, 95% CI 1.51-1.93; I
conclusionsIndividuals with PRISm have a significantly increased risk of mortality compared with those with normal spirometry.
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