ArticleScience advances2023
Severe acute malnutrition promotes bacterial binding over proinflammatory cytokine secretion by circulating innate immune cells.
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Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
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Who cites it
17 citing papers in PubMed, 11 citations in OpenAlex.
- Immune responses to topical emollient therapy with sunflower seed oil in young children with severe acute malnutrition in Bangladesh: a randomized controlled trial.Pediatric research · 2026Trial
- Role of bacterial outer membrane vesicles in immune evasion during infection.Archives of microbiology · 2026Review
- Intestinal Permeability Is Associated with Mortality and Readmission in Children Hospitalized with Severe Acute Malnutrition.The Journal of nutrition · 2026Observational
- Restoration of anti-bacterial innate immune cell function lags behind nutritional recovery among children convalescing from complicated severe acute malnutrition.Nature communications · 2026Article
- Identifying populations with high prevalence of non-malarial febrile illnesses across different demographic groups in Malawi.Malaria journal · 2026Article
- Association of malnutrition with in-hospital outcomes among patients hospitalized with dermatomyositis or polymyositis.Clinical rheumatology · 2026Article
- Multiomics characterization of acute child illness and mortality in Africa and South Asia.Nature communications · 2026Article
- Hypoalbuminemia induces immunosuppression through disorder in macrophages and drives resistance to immune checkpoint inhibitors.Cancer immunology, immunotherapy : CII · 2026Article
- Article
- Article
- Long-Term Intestinal Epithelial Remodeling Induced by Acute Protein-Energy Malnutrition.bioRxiv : the preprint server for biology · 2025Article
- Mechanisms conferring multi-layered protection against intestinal Salmonella Typhimurium infection.FEMS microbiology reviews · 2025Review
- Mpox after COVID-19 in Africa: Different epidemic, similar challenges.Journal of public health in Africa · 2025Article
- Sepsis with Cancer is Marked by a Dysregulated Myeloid Cell Compartment: A Pilot Study.Journal of inflammation research · 2025Article
- Association between controlling nutritional status score and mortality in older patients with dysphagia in Japan:Frontiers in nutrition · 2025Article
- Mitochondrial perturbations in low-protein-diet-fed mice are associated with altered neutrophil development and effector functions.Cell reports · 2024Article
- Novel gastrointestinal tools (GI Tools) for evaluating gut functional capacity in adults with environmental enteropathy in Zambia and Zimbabwe: A cross-sectional study protocol.F1000Research · 2024Article
Corrections and comments
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Authors and funding
28 authors at 4 institutions in 3 countries.
Tracy N PhiriTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0001-7110-3347
Kuda MutasaZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0003-4158-6282
Sandra RukoboZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0009-0009-2077-666X
Margaret GovhaZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
Patience MushayanembwaZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0001-7640-4413
Simutanyi MwakamuiTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0001-7667-6531
Tafhima HaiderBlizard Institute, Queen Mary University of London, London, UK.ORCID 0000-0003-0077-3970
Kanekwa ZyamboTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0001-5686-5319
Cherlynn DumburaZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0002-1704-0274
Joice TomeZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
Thompson RunodamotoZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
Leah ChidambaZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
Florence D MajoZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0009-0006-1282-0462
Deophine NgosaTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0002-9019-9046
Kanta ChandweTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0003-1403-8432
Chanda KapomaTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0001-6404-1686
Benjamin MwapenyaZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
Wadzanai MufukariZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.
Jonathan P SturgeonZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0003-1318-1739
Ruairi C RobertsonBlizard Institute, Queen Mary University of London, London, UK.ORCID 0000-0002-3719-2056
Melanie SmukBlizard Institute, Queen Mary University of London, London, UK.ORCID 0000-0002-1594-1458
Robert NtoziniZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0002-8543-2835
Kusum NathooDepartment of Paediatrics and Child Health, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe.
Beatrice AmadiTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0001-6363-2943
Paul KellyTropical Gastroenterology and Nutrition group (TROPGAN), University of Zambia School of Medicine, Lusaka, Zambia.ORCID 0000-0003-0844-6448
Mutsa Bwakura-DangarembiziZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0001-7751-6177
Andrew J PrendergastZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0001-7904-7992
Claire D BourkeZvitambo Institute for Maternal and Child Health Research, Harare, Zimbabwe.ORCID 0000-0002-7244-0895
Zvitambo Institute for Maternal and Child Health Research · ZWQueen Mary University of London · GBUniversity of Zambia · ZMUniversity of Zimbabwe · ZW
Funding
Medical Research Council MR/K012711/1Wellcome Trust 206455/Z/17/Z
Abstract
Children with severe acute malnutrition (SAM) have high infectious mortality and morbidity, implicating defects in their immune defenses. We hypothesized that circulating innate immune cells from children (0 to 59 months) hospitalized with SAM in Zambia and Zimbabwe (
Indexed as
Severe Acute MalnutritionBacteriaChildCytokinesHumansImmunity, InnatePatient DischargeCytokines
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.