Evidence map›Paper›PMID 37910592›Full record

SynthesisPLoS neglected tropical diseases2023

A systematic review of neglected tropical diseases (NTDs) in Myanmar.

Myo Maung Maung Swe, Aung Pyae Phyo, Ben S Cooper, Nicholas J White, Frank Smithuis, Elizabeth A Ashley

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Exploring theResearch and practice in thrombosis and haemostasis · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Myo Maung Maung SweMyanmar Oxford Clinical Research Unit (MOCRU), Yangon, Myanmar.ORCID 0000-0002-6044-8718
Aung Pyae PhyoMyanmar Oxford Clinical Research Unit (MOCRU), Yangon, Myanmar.
Ben S CooperCentre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Nicholas J WhiteCentre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Frank SmithuisMyanmar Oxford Clinical Research Unit (MOCRU), Yangon, Myanmar.
Elizabeth A AshleyCentre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom.
Mahidol University · THUniversity of Oxford · GBMahosot Hospital · LA

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundNeglected tropical diseases (NTDs) affect most impoverished communities in developing countries, like Myanmar in Southeast Asia. NTDs have been understudied and underreported in Myanmar.

methodsA systematic review of published and grey literature (1900-2023) on neglected tropical diseases (NTDs) in Myanmar was conducted. The literature search included five international databases: PubMed, EMBASE, Ovid Global Health, and Web of Science Core Collection and one national database: the Myanmar Central Biomedical Library (locally published papers and grey literature). The selection criteria included articles with all types of study designs of current or previous infections conducted in humans, that reported NTDs, recognised by WHO, US CDC, and listed in PLoS NTDs. We included melioidosis and rickettsioses which we consider also meet the definition of an NTD.

resultsA total of 5941 records were retrieved and screened, of which, 672 (11%) met the selection criteria and were included in this review. Of the included articles, 449 (65%) were published after 2000 and 369 (55%) were from two regions (Yangon and Mandalay) of Myanmar. Of the included articles, 238 (35%) reported bacterial NTDs, 212 (32%) viral NTDs, 153 (23%) helminth NTDs, 25 (4%) protozoal NTDs and 39 (6%) reported more than one aetiology. Based on reported frequency in descending order, the bacterial NTDs were leprosy, Escherichia coli enteritis, salmonellosis, cholera, shigellosis, melioidosis, leptospirosis and rickettsioses; the viral NTDs were dengue, chikungunya and Japanese encephalitis virus (JEV) infection; the protozoal NTDs were amoebiasis, giardiasis and leishmaniasis, and the helminth NTDs were ascariasis, trichuriasis, hookworm disease, filariasis and strongyloidiasis.

conclusionThis review summarises NTDs reported in Myanmar over the past 100 years. The findings suggest that most NTDs are likely to be under reported, especially from the majority of the country which is far from academic centres. Research capacity building together with strengthening of laboratory systems would lead to better understanding of the true burden of NTDs in Myanmar.

trial registrationPROSPERO registration ID: CRD42018092627.

Indexed as

AscariasisEncephalitis, JapaneseHelminthsMelioidosisRickettsia InfectionsTropical MedicineAnimalsHumansMyanmarNeglected Diseases

Identifiers

PMID37910592
PMCPMC10619876
OpenAlexW4388126010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.