Evidence map›Paper›PMID 37910515›Full record

ArticlePloS one2023

Exposure to low levels of hydrogen sulphide and its impact on chronic obstructive pulmonary disease and lung function in the geothermal area of Mt. Amiata in Italy: The cross-sectional InVETTA study.

Giorgia Stoppa, Daniela Nuvolone, Davide Petri, Letizia Centi, Francesca Nisticò, Emanuele Crocetti, Fabio Barbone, Fabio Voller

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Giorgia StoppaUnit of Epidemiology, Regional Health Agency of Tuscany, Florence (FI), Italy.ORCID 0000-0002-4272-2672
Daniela NuvoloneUnit of Epidemiology, Regional Health Agency of Tuscany, Florence (FI), Italy.
Davide PetriUnit of Epidemiology, Regional Health Agency of Tuscany, Florence (FI), Italy.
Letizia CentiHealth Agency of South-East Tuscany, Arezzo (AR), Italy.
Francesca NisticòHealth Agency of South-East Tuscany, Arezzo (AR), Italy.
Emanuele CrocettiUnit of Epidemiology, Regional Health Agency of Tuscany, Florence (FI), Italy.
Fabio BarboneDepartment of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy.
Fabio VollerUnit of Epidemiology, Regional Health Agency of Tuscany, Florence (FI), Italy.
University of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe geothermal power plants for electricity production currently active in Italy are all located in Mt. Amiata area in the Tuscany region. A cross-sectional survey was conducted in the framework of the regional project "InVETTA-Biomonitoring Survey and Epidemiological Evaluations for the Protection of Health in the Amiata Territories", using objective measures of lung function to investigate the role of hydrogen sulphide (H2S) in affecting the respiratory health of the population living in this area.

methods2018 adults aged 18-70 were enrolled during 2017-2019. Home and workplace addresses of participants were geocoded. Dispersion modelling was used to evaluate the spatial variability of exposure to H2S from the geothermal power plants' emissions. We estimated average long-term historical exposure to H2S and more recent exposure indicators. Chronic Obstructive Pulmonary Disease (COPD) was defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD). Multivariable logistic regressions were performed to investigate associations between outcome and exposure.

resultsOur findings did not showed any evidence of an association between increasing H2S exposure and lung function impairments. Some risk reductions were observed: a -32.8% (p = 0.003) for FEV1<80% and a -51.7% (p = 0.001) risk decrease for FVC<80% were associated with interquartile increase (13.8 μg/m3) of H2S levels.

conclusionOur study provides no evidence that chronic exposure to low levels of H2S is associated with decrements in pulmonary function, suggesting that ambient H2S exposure may benefit lung function.

Indexed as

Hydrogen SulfidePulmonary Disease, Chronic ObstructiveAdultCross-Sectional StudiesHumansItalyLungHydrogen Sulfide

Identifiers

PMID37910515
PMCPMC10619772
OpenAlexW4388126041

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.