Evidence map›Paper›PMID 37910479›Full record

ArticleGut microbes2023

Fecal short-chain fatty acids in non-constipated irritable bowel syndrome: a potential clinically relevant stratification factor based on catabotyping analysis.

Giorgio Gargari, Giacomo Mantegazza, Valentina Taverniti, Claudio Gardana, Alice Valenza, Federico Rossignoli, Maria Raffaella Barbaro, Giovanni Marasco, Cesare Cremon, Giovanni Barbara and 1 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

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  7. Diarrhea management: from pathophysiology to microbiota modulation.Therapeutic advances in gastroenterology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Giorgio GargariDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.ORCID 0000-0001-9077-6328
Giacomo MantegazzaDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.ORCID 0000-0002-0936-1211
Valentina TavernitiDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.
Claudio GardanaDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.
Alice ValenzaDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.
Federico RossignoliDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.
Maria Raffaella BarbaroDipartimento di Scienze Mediche e Chirurgiche, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Giovanni MarascoDipartimento di Scienze Mediche e Chirurgiche, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Cesare CremonDipartimento di Scienze Mediche e Chirurgiche, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Giovanni BarbaraDipartimento di Scienze Mediche e Chirurgiche, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Simone GuglielmettiDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.ORCID 0000-0002-8673-8190
University of Milan · ITAzienda USL di Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota is believed to be a critical factor in the pathogenesis of IBS, and its metabolic byproducts, such as short-chain fatty acids (SCFAs), are known to influence gut function and host health. Despite this, the precise role of SCFAs in IBS remains a topic of debate. In this study, we examined the bacterial community structure by 16S rRNA gene profiling and SCFA levels by UPLC-MS/MS in fecal samples from healthy controls (HC;

Indexed as

Gastrointestinal MicrobiomeIrritable Bowel SyndromeChromatography, LiquidDiarrheaFatty Acids, VolatileFecesHumansRNA, Ribosomal, 16STandem Mass SpectrometryFatty Acids, VolatileRNA, Ribosomal, 16Sabdominal painbutyratecatabotypingdiarrheafecal microbiomefecal typeGastrointestinal disordermetataxonomicssuccinatevalerate

Identifiers

PMID37910479
PMCPMC10773536
OpenAlexW4388126707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.