Evidence map›Paper›PMID 37910377›Full record

ArticlePharmacoEconomics2024

Cost-Effectiveness Analysis of Vaccines for COVID-19 According to Sex, Comorbidity and Socioeconomic Status: A Population Study.

Javier Mar, Oliver Ibarrondo, Carlo Delfin S Estadilla, Nico Stollenwerk, Fernando Antoñanzas, Rubén Blasco-Aguado, Igor Larrañaga, Joseba Bidaurrazaga, Maíra Aguiar

Abstract read
In one paragraph

Article in PharmacoEconomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Javier MarResearch Unit, Osakidetza Basque Health Service, Debagoiena Integrated Health Organization, Arrasate-Mondragón, Spain. javier.marmedina@gmail.com.ORCID 0000-0002-9455-4869
Oliver IbarrondoResearch Unit, Osakidetza Basque Health Service, Debagoiena Integrated Health Organization, Arrasate-Mondragón, Spain.
Carlo Delfin S EstadillaBasque Center for Applied Mathematics, Bilbao, Spain.
Nico StollenwerkBasque Center for Applied Mathematics, Bilbao, Spain.
Fernando AntoñanzasDepartamento de Economía, Universidad de La Rioja, Logroño, Spain.
Rubén Blasco-AguadoBasque Center for Applied Mathematics, Bilbao, Spain.
Igor LarrañagaResearch Unit, Osakidetza Basque Health Service, Debagoiena Integrated Health Organization, Arrasate-Mondragón, Spain.
Joseba BidaurrazagaPublic Health Directorate, Basque Government Health Department, Bilbao, Spain.
Maíra AguiarBasque Center for Applied Mathematics, Bilbao, Spain.

Funding

Berrikuntza + Ikerketa + Osasuna Eusko Fundazioa BIO21/COV/001Hezkuntza, Hizkuntza Politika Eta Kultura Saila, Eusko Jaurlaritza Mathematical Modeling Applied to Health" ProjectHezkuntza, Hizkuntza Politika Eta Kultura Saila, Eusko Jaurlaritza the BERC 2022-2025 programme
6 · The paper itself

Abstract

BACKGROUND AND

objectiveCoronavirus disease 2019 (COVID-19) vaccines are extremely effective in preventing severe disease, but their real-world cost effectiveness is still an open question. We present an analysis of the cost-effectiveness and economic impact of the initial phase of the COVID-19 vaccination rollout in the Basque Country, Spain.

methodsTo calculate costs and quality-adjusted life years for the entire population of the Basque Country, dynamic modelling and a real-world data analysis were combined. Data on COVID-19 infection outcomes (cases, hospitalisations, intensive care unit admissions and deaths) and population characteristics (age, sex, socioeconomic status and comorbidity) during the initial phase of the vaccination rollout, from January to June of 2021, were retrieved from the Basque Health Service database. The outcomes in the alternative scenario (without vaccination) were estimated with the dynamic model used to guide public health authority policies, from February to December 2020. Individual comorbidity-adjusted life expectancy and costs were estimated.

resultsBy averting severe disease-related outcomes, COVID-19 vaccination resulted in monetary savings of €26.44 million for the first semester of 2021. The incremental cost-effectiveness ratio was €707/quality-adjusted life year considering official vaccine prices and dominant real prices. While the analysis by comorbidity showed that vaccines were considerably more cost effective in individuals with pre-existing health conditions, this benefit was lower in the low socioeconomic status group.

conclusionsThe incremental cost-effectiveness ratio of the vaccination programme justified the policy of prioritising high-comorbidity patients. The initial phase of COVID-19 vaccination was dominant from the perspective of the healthcare payer.

Indexed as

COVID-19VaccinesComorbidityCost-Benefit AnalysisCost-Effectiveness AnalysisCOVID-19 VaccinesHumansSocial ClassVaccinationCOVID-19 VaccinesVaccines

Identifiers

PMID37910377
PMCPMC10810962

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.